Abstract
Cardiovascular disease (CVD) is the leading cause of death worldwide. There are several social and environmental circumstances that influence mortality and outcomes related to the progression of CVD. Thus, understanding the relationship between social determinants of health (SDoH) and CVD is crucial in developing measures to manage and prevent adverse outcomes. The associations of SDoH and CVD are complex and continue to evolve in relation to ongoing investigations. This chapter reviews the well-delineated traditional components of SDoH and their relationships with CVD, while exploring other social factors, societal influence, and the effects of cultural standing in relation to CVD risk and outcome.