Abstract
Several advances in diagnosis, treatment and palliation of pancreatic cancer have occurred in the last decade. A multidisciplinary approach of the management of pancreatic cancer is required. Cross sectional imaging is usually the first imaging modality for diagnosis and staging. Endoscopic ultrasonography (EUS) with its superiority in detecting smaller lesions, lymph node metastasis, and vascular infiltration has become the next imaging modality. The adjunction of fine needle aspiration to EUS, with its relatively low risk profile, has increased the accuracy of this technique and helped differentiate pancreatic adenocarcinoma from other pancreatic neoplasms which may influence treatment as well as prognosis. Finally, EUS-FNA allows the performance of celiac plexus neurolysis for unremitting pain in these patients.