Abstract
A recent meta-analysis of 16 publications suggests that bone mineral density (BMD) is not associated with vitamin D receptor (VDR) gene polymorphism (VDRGP), p > 0.05, at all sites analyzed when false positive studies are excluded [7]. Although more papers are being published, results are still conflicting. We re-addressed this issue with an approach using two methods involving fuzzy mathematics, [4]. Fifty-five publications on spinal BMD were analyzed as were 73 publications on hip BMD. In this paper, an analysis by belief functions seems to confirm the findings of [4]. This analysis suggests that spinal BMD is associated with VDRGP in females before or after menopause. This BMD - VDR association is also evident in studies in populations males and females combined.