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Optical detection of structural changes in atherosclerotic plaque
Conference proceeding

Optical detection of structural changes in atherosclerotic plaque

R. M. Korol, P. B. Canham, H. M. Finlay, R. R. Hammond, M. Quantz, G. G. Ferguson and A. R. Lucas
Optics InfoBase Conference Papers; European Conference on Biomedical Optics, ECBO 2005, Vol.12 June 2005 through 12 June 2005
2005

Abstract

Atherosclerosis Collagen Elastin Fluorescence spectroscopy Plaque morphology Vascular remodeling Glycoproteins Musculoskeletal system Spectroscopic analysis Atherosclerotic plaque Collagen type I Compositional changes Connective tissues Optical detection
We have demonstrated that in vitro fluorescence spectroscopic analysis of diseased carotid arteries can identify clinically relevant compositional changes in connective tissue (collagen type I, III, IV and elastin) associated with plaque remodeling and instability. © 2005 Optical Society of America.

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