Abstract
Gannon’s (1) concept of homeostasis seems physiologically and pathologically unrelated to the general tissue hormone of corticoida as put forth by Hartmann and coworkers (2). In the same light, diversification seems to be at hand in a comparison of the maladie poatoperatorie as noted by the French surgeon Rene Leriche (3), and Claude Bernard’s (4) concept of the consistency within the milieu interieur. | Yet, through the effort of Selye (5) these seemingly unrelated observations were woven together into the General-Adaptation-Syndrome after he realized that all living organisms respond to stress in an identical fashion, and that such reaction patterns, or adaptive reactions, are identical irrespective of the stressing agent.