Abstract
Peripheral intravenous infiltration is a complication that can cause serious morbidities and adversely affect healthcare outcomes. Ideally, the best way to avoid peripheral intravenous infiltrations is to prevent them with astute nursing assessment and practices. However, infiltrations occur despite adequate prevention measures. Prompt identification and treatment utilizing appropriate tools and pathways is necessary to minimize complications. Neonates are specifically vulnerable to infiltrations, but many grading tools and interventions are not developmentally appropriate for all populations. By adopting a population-specific nursing protocol that addresses prevention, timely assessment and intervention, outcomes will be positively influenced in the neonatal intensive care unit.