Abstract
[No Abstract, using the opening paragraph]|Epilepsy is a chronic, broad spectrum neurological disease which is characterized by recurrent and unprovoked seizures (Fisher et al. 2014). It is the fourth most common neurological disease affecting approximately 50 million people globally (Leonardi and Ustun 2002). In fact, it is estimated that about 1 in 26 people in the United States, will develop epilepsy during some point in their lifetime (Hesdorffer et al. 2011). The pathophysiology of epilepsy and seizures involves a chronic hyper excitability of the brain caused by hyperactive and hyper synchronous neuronal firing. This increase in neuronal excitability in epilepsy may be caused by a varied range of factors, channelopathies, and alterations in synaptic transmission, changes in levels of neurosteroids or neuropeptides or metabolic disorders. These abnormal changes may be the resultant of genetic abnormalities and developmental disorders, brain injury or trauma, stress or may be idiopathic in nature (Berg and Scheffer 2011; Shorvon 2011).