A Structure-based Design Approach for Generating High Affinity BRD4 D1-Selective Chemical Probes

Huarui Cui; Anand Divakaran; Zachariah J. Hoell; Mikael O. Ellingson; Cole R. Scholtz; Huda Zahid; Jorden A. Johnson; Elizabeth C. Griffith; Clifford T. Gee; Amani L. Lee; Shalil Khanal; Ke Shi; Hideki Aihara; Vijay H. Shah; Richard E. Lee; Daniel A. Harki; William C. K. Pomerantz

doi:10.1021/acs.jmedchem.1c01779

Journal article

A Structure-based Design Approach for Generating High Affinity BRD4 D1-Selective Chemical Probes

Huarui Cui, Anand Divakaran, Zachariah J. Hoell, Mikael O. Ellingson, Cole R. Scholtz, Huda Zahid, Jorden A. Johnson, Elizabeth C. Griffith, Clifford T. Gee, Amani L. Lee, …

Journal of Medicinal Chemistry, Vol.65(3)

2022

DOI: https://doi.org/10.1021/acs.jmedchem.1c01779

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Title: A Structure-based Design Approach for Generating High Affinity BRD4 D1-Selective Chemical Probes
Creators: Huarui Cui - University of Minnesota
Anand Divakaran - University of Minnesota
Zachariah J. Hoell - University of Minnesota
Mikael O. Ellingson - University of Minnesota
Cole R. Scholtz - University of Minnesota
Huda Zahid - University of Minnesota
Jorden A. Johnson
Elizabeth C. Griffith - St. Jude Children's Research Hospital
Clifford T. Gee - St. Jude Children's Research Hospital
Amani L. Lee - Mayo Clinic
Shalil Khanal - Mayo Clinic
Ke Shi - University of Minnesota
Hideki Aihara - University of Minnesota
Vijay H. Shah - Mayo Clinic
Richard E. Lee - St. Jude Children's Research Hospital
Daniel A. Harki - University of Minnesota
William C. K. Pomerantz - University of Minnesota
Publication Details: Journal of Medicinal Chemistry, Vol.65(3)
Identifiers: 991006062466202656
Academic Unit: Chemistry and Biochemistry
Resource Type: Journal article

A Structure-based Design Approach for Generating High Affinity BRD4 D1-Selective Chemical Probes

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