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A TRUE MALIGNANT SCHWANNOMA OF THE EIGHTH CRANIAL NERVE
Journal article   Peer reviewed

A TRUE MALIGNANT SCHWANNOMA OF THE EIGHTH CRANIAL NERVE

L. Fernando Gonzalez, Gregory P. Lekovic, Jennifer Eschbacher, Stephen Coons and Robert F. Spetzler
Neurosurgery, Vol.61(2), pp.E421-E422
08/01/2007

Abstract

Malignant schwannoma Acoustic neuroma Malignant nerve peripheral tumors Cranial nerve
Abstract OBJECTIVE The clinical presentation, pathology, treatment, and outcome of a 43-year-old woman with a malignant peripheral nerve sheath tumor arising from a benign schwannoma of the eighth cranial nerve are presented. CLINICAL PRESENTATION Initially, the tumor was debulked. After finding malignant areas within the benign tumor, it was considered to be a malignant transformation of a previously benign tumor. INTERVENTION Aggressive total resection was obtained during a second-stage procedure. Postoperatively, the tumor bed was radiated for palliation. CONCLUSION Despite surgery, radiation, and chemotherapy, the patient died rapidly as a result of disseminated metastatic disease.

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