Abstract
IntroductionIn recent years, octogenarian population (≥80 years) has been increasingly referred for percutaneous coronary intervention (PCI). However, the outcome of octogenarian compared with younger population is unknown. Therefore, we sought to compare in-hospital clinical outcomes after PCI for octogenarian compared with non-octogenarian patients.MethodsUsing national inpatient sampling (NIS), we identified all octogenarian patients who underwent PCI and compared with patients who are younger than 80 years old.ResultsA total of 1544563 octogenarian patients (mean age 83.96 ± 3.29 years, 50.1% women) and 9511996 non-octogenarian patients (mean age 62.28 ± 11.04 years, 34% women) were identified. After multivariate adjustment, octogenarians had higher in-hospital mortality (3.3% vs 1.3% adjusted Odds Ratio [aOR], 1.62; 95% CI, 1.60-1.64, P<0.0001), longer LOS (3 vs. 2 days, p<0.0001), higher cardiac complications (3.4% vs. 2.4% aOR 1.07; 95% CI 1.06 to 1.08; p < 0.0001), permanent pacemaker implantation (1.4% vs. 0.4% aOR 1.94; 95% CI 1.94 to 1.98; p<0.0001), post-procedural stroke (6.3% vs. 3.8% aOR 1.32; 95% CI 1.32 to 1.33; p < 0.0001) and hemorrhage requiring transfusion (2.1% vs. 1.0% aOR 1.301 ; 95% CI 1.281 to 1.281; p < 0.0001).ConclusionsOverall, octogenarian patients who underwent PCI were at increased risk for in-hospital mortality and morbidity compared to non-octogenarians. The decision to proceed with PCI in this patient population should be individualized taking into consideration, known risk factors and expected impact on quality of life.