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Acellular Dermal Matrix as a Definitive Reconstructive Option for Management of a Large Myelomeningocele Defect in the Setting of Severe Lumbar Kyphosis
Journal article   Peer reviewed

Acellular Dermal Matrix as a Definitive Reconstructive Option for Management of a Large Myelomeningocele Defect in the Setting of Severe Lumbar Kyphosis

Srinivas M. Susarla, Jason Hauptman, Russell Ettinger, Bay Sittler and Richard G. Ellenbogen
World Neurosurgery, Vol.129
2019

Abstract

Acellular Dermis Humans Infant, Newborn Kyphosis Lumbar Vertebrae Meningomyelocele Reconstructive Surgical Procedures bacitracin Arnold Chiari malformation Article blood transfusion brain ventricle peritoneum shunt breech presentation case report clinical article epithelization female human hydramnios hydrocephalus kyphosis meningomyelocele neural tube defect newborn soft tissue spine surgery surgical risk acellular dermal matrix complication kyphosis lumbar vertebra meningomyelocele procedures reconstructive surgery
Background: Severe kyphosis is infrequently seen in neonates with myelomeningoceles. Spinal skeletal dysmorphology complicates repair, as local tissue may be insufficient to cover the dural repair. Although neonatal kyphectomy has been proposed as a potential solution to this problem, it carries significant potential risks that may not be acceptable to families. Case Description: A neonate presented with a large myelomeningocele defect with associated severe lumbar kyphosis. Kyphectomy was both declined by the family owing to the potential surgical risks and deemed not appropriate by the surgeons based on the challenging anatomic considerations. Soft tissue closure was not possible with local tissue rearrangement. Acellular dermal matrix was used as a definitive soft tissue coverage option, with complete epithelialization noted at 8 weeks postoperatively. Conclusions: Acellular dermal matrix is a potentially useful adjunct for definitive reconstruction of complex neonatal soft tissue defects where local tissue is not available. © 2019 Elsevier Inc.

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