Alirocumab in Patients With Polyvascular Disease and Recent Acute Coronary Syndrome ODYSSEY OUTCOMES Trial

J Wouter Jukema; Michael Szarek; Laurien E Zijlstra; H Asita de Silva; Deepak L Bhatt; Vera A Bittner; Rafael Diaz; Jay M Edelberg; Shaun G Goodman; Corinne Hanotin; Robert A Harrington; Yuri Karpov; Angle Moryusef; Robert Pordy; Juan C Prieto; Matthew T Roe; Harvey D White; Andreas M Zeiher; Gregory G Schwartz; P Gabriel Steg; Pierluigi Tricoci; Kenneth W Mahaffey; Guillaume Lecorps; Angele Moryusef; William J Sasiela; Jean-Francois Tamby; Philip E Aylward; Heinz Drexel; Peter Sinnaeve; Mirza Dilic; Nina N Gotcheva; Juan-Carlos Prieto; Huo Yong; Patricio Lopez-Jaramillo; Ivan Pecin; Zeljko Reiner; Petr Ostadal; Steen Hvitfeldt Poulsen; Margus Viigimaa; Markku S Nieminen; Nicolas Danchin; Vakhtang Chumburidze; Nikolaus Marx; Evangelos Liberopoulos; Pablo Carlos Montenegro Valdovinos; Hung-Fat Tse; Robert Gabor Kiss; Denis Xavier; Doron Zahger; Marco Valgimigli; Takeshi Kimura; Hyo Soo Kim; Sang-Hyun Kim; Sasko Kedev; Andrejs Erglis; Aleksandras Laucevicius; Khalid Yusoff; Ramos Lopez; Gabriel Arturo Ramos Lopez; Marco Alings; Sigrun Halvorsen; Roger M Correa Flores; Rody G Sy; Andrzej Budaj; Joao Morais; Maria Dorobantu; Arsen D Ristic; Terrance Chua; Jan Murin; Zlatko Fras; Anthony J Dalby; Jose Tunon; Emil Hagstrom; Christian Muller; Chern-En Chiang; Piyamitr Sritara; Sema Guneri; Alexander Parkhomenko; Kausik K Ray; Patrick M Moriarty; Bernard Chaitman; Sheryl F Kelsey; Anders G Olsson; Jean-Lucien Rouleau; Maarten L Simoons; Karen Alexander; Chiara Meloni; Robert Rosenson; Eric JG Sijbrands; John H Alexander; Luciana Armaganijan; Akshay Bagai; Maria Cecilia Bahit; J Matthew Brennan; Shaun Clifton; Adam D DeVore; Shalonda Deloatch; Sheila Dickey; Keith Dombrowski; Gregory Ducrocq; Zubin Eapen; Patricia Endsley; Arleen Eppinger; Robert W Harrison; Connie Ng Hess; Mark A Hlatky; Joseph Dedrick Jordan; Joshua W Knowles; Bradley J Kolls; David F Kong; Sergio Leonardi; Linda Lillis; David J Maron; Jill Marcus; Robin Mathews; Rajendra H Mehta; Robert J Mentz; Humberto Graner Moreira; Chetan B Patel; Sabrina Bernardez Pereira; Lynn Perkins; Thomas J Povsic; Etienne Puymirat; William Schuyler Jones; Bimal R Shah; Matthew W Sherwood; Kenya Stringfellow; Darin Sujjavanich; Mustafa Toma; Sean FP Van Diepen; Matthew D Wilson; Andrew Tze-Kay Yan; Renato D Lopes; Charlene Trotter; Lilia B Schiavi; Marcelo Garrido; Andres F Alvarisqueta; Sonia A Sassone; Anselmo P Bordonava; Alberto E Alves De Lima; Jorge M Schmidberg; Ernesto A Duronto; Orlando C Caruso; Leonardo P Novaretto; Miguel Angel Hominal; Oscar R Montana; Alberto Caccavo; Oscar A Gomez Vilamajo; Alberto J Lorenzatti; Luis R Cartasegna; Gustavo A Paterlini; Ignacio J Mackinnon; Guillermo D Caime; Marcos Amuchastegui; Rodolfo Salomone; Oscar R Codutti; Horacio O Jure; Julio OE Bono; Adrian D Hrabar; Julio A Vallejos; Rodolfo A Ahuad Guerrero; Federico Novoa; Cristian A Patocchi; Cesar J Zaidman; Maria E Giuliano; Ricardo D Dran; Marisa L Vico; Gabriela S Carnero; Pablo N Guzman; Juan C Medrano Allende; Daniela F Garcia Brasca; Miguel H Bustamante Labarta; Sebastian Nani; Eduardo DS Blumberg; Hugo R Colombo; Alberto Liberman; Hector L Luciardi; Gabriel D Waisman; Mario A Berli; Ruben O Garcia Duran; Horacio G Cestari; Hugo A Luquez; Jorge A Giordano; Silvia S Saavedra; Gerardo Zapata; Osvaldo Costamagna; Susana Llois; Jonathon H Waites; Nicholas Collins; Allan Soward; Chris LS Hii; James Shaw; Margaret A Arstall; John Horowitz; James F Rogers; David Colquhoun; Romulo E Oqueli Flores; Philip Roberts-Thomson; Owen Raffel; Sam J Lehman; Constantine Aroney; Steven GM Coverdale; Paul J Garrahy; Gregory Starmer; Mark Sader; Patrick A Carroll; Ronald Dick; Robert Zweiker; Uta Hoppe; Kurt Huber; Rudolf Berger; Franz Weidinger; Dirk Faes; Kurt Hermans; Bruno Pirenne; Attilio Leone; Etienne Hoffer; Mathias CM Vrolix; Luc De Wolf; Bart Wollaert; Marc Castadot; Karl Dujardin; Christophe Beauloye; Geert Vervoort; Harry Striekwold; Carl Convens; John Roosen; Emanuele Barbato; Marc Claeys; Frank Cools; Ibrahim Terzic; Fahir Barakovic; Zlatko Midzic; Belma Pojskic; Emir Fazlibegovic; Azra Durak-Nalbantic; Dusko Vulic; Adis Muslibegovic; Boris Goronja; Gilmar Reis; Luciano Sousa; Jose C Nicolau; Flavio E Giorgeto; Ricardo P Silva; Lilia Nigro Maia; Rafael Rech; Paulo RF Rossi; Maria Jose AG Cerqueira; Norberto Duda; Renato Kalil; Adrian Kormann; Jose Antonio M Abrantes; Pedro Pimentel Filho; Ana Priscila Soggia; Mayler ON de Santos; Fernando Neuenschwander; Luiz C Bodanese; Yorghos L Michalaros; Freddy G Eliaschewitz; Maria H Vidotti; Paulo E Leaes; Roberto V Botelho; Sergio Kaiser; Euler Roberto F Fernandes Manenti; Dalton B Precoma; Jose C Moura Jorge; Pedro GM de B Silva; Jose A Silveira; Wladmir Saporito; Jose A Marin Neto; Gilson S Feitosa; Luiz Eduardo F Ritt; Juliana A de Souza; Fernando Costa; Weimar KSB Souza; Helder JL Reis; Leandro Machado; Jose Carlos Aidar Ayoub; Georgi V Todorov; Fedya P Nikolov; Elena S Velcheva; Maria L Tzekova; Haralambi O Benov; Stanislav L Petranov; Haralin S Tumbev; Nina S Shehova-Yankova; Dimitar T Markov; Dimitar H Raev; Mihail N Mollov; Kostadin N Kichukov; Katya A Ilieva-Pandeva; Raya Ivanova; Valentina M Mincheva; Petar V Lazov; Bojidar I Dimov; Manohara Senaratne; James Stone; Jan Kornder; Stephen Pearce; Danielle Dion; Daniel Savard; Yves Pesant; Amritanshu Pandey; Simon Robinson; Gilbert Gosselin; Saul Vizel; Gordon Hoag; Ronald Bourgeois; Anne Morisset; Eric Sabbah; Bruce Sussex; Simon Kouz; Paul MacDonald; Ariel Diaz; Nicolas Michaud; David Fell; Raymond Leung; Tycho Vuurmans; Christopher Lai; Frank Nigro; Richard Davies; Gustavo Nogareda; Ram Vijayaraghavan; John Ducas; Serge Lepage; Shamir Mehta; James Cha; Robert Dupuis; Peter Fong; Josep Rodes-Cabau; Hussein Fadlallah; David Cleveland; Huynh Thao; Iqbal Bata; Adnan Hameed; Cristian Pincetti; Sergio Potthoff; Monica Acevedo; Arnoldo Aguirre; Margarita Vejar; Mario Yanez; Guillermo Araneda; Mauricio Fernandez; Luis Perez; Paola Varleta; Fernando Florenzano; Laura Huidobro; Carlos A Raffo; Claudia Olivares; Leonardo Nahuelpan; Humberto Montecinos; Jiyan Chen; Yugang Dong; Weijian Huang; Jianzhong Wang; Shi'An Huang; Zhuhua Yao; Xiang Li; Lan Cui; Wenhua Lin; Yuemin Sun; Jingfeng Wang; Jianping Li; Xuelian Zhang; Hong Zhu; Dandan Chen; Lan Huang; Shaohong Dong; Guohai Su; Biao Xu; Xi Su; Xiaoshu Cheng; Jinxiu Lin; Wenxia Zong; Huanming Li; Yi Feng; Dingli Xu; Xinchun Yang; Yuannan Ke; Xuefeng Lin; Zheng Zhang; Zeqi Zheng; Zhurong Luo; Yundai Chen; Chunhua Ding; Yang Zheng; Xiaodong Li; Daoquan Peng; Ying Li; Meng Wei; Shaowen Liu; Yihua Yu; Baiming Qu; Weihong Jiang; Yujie Zhou; Xingsheng Zhao; Zuyi Yuan; Ying Guo; Xiping Xu; Xubo Shi; Junbo Ge; Guosheng Fu; Feng Bai; Weiyi Fang; Xiling Shou; Xiangjun Yang; Jian'An Wang; Yingxian Sun; Qinghua Lu; Ruiyan Zhang; Jianhua Zhu; Yizhou Xu; Zhongcai Fan; Tianchang Li; Chun Wu; Nicolas Jaramillo; Gregorio Sanchez Vallejo; Diana C Luna Botia; Rodrigo Botero Lopez; Dora I Molina De Salazar; Alberto J Cadena Bonfanti; Juan Diego Higuera; Sandra I Barrera Silva; Henry J Garcia Lozada; Julian A Coronel Arroyo; Jose L Accini Mendoza; Ricardo L Fernandez Ruiz; Fernando G Manzur Jatin; Aristides Sotomayor Herazo; Jeffrey Castellanos Parada; Miguel A Urina Triana; Maja Strozzi; Sinisa Car; Davor Milicic; Martina Lovric Bencic; Hrvoje Pintaric; Deiti Prvulovic; Jozica Sikic; Viktor Persic; Dean Mileta; Kresimir Stambuk; Babic Zdravko; Vjekoslav Tomulic; Stanka Mejic Krstulovic; Boris Starcevic; Jindrich Spinar; David Horak; Josef Stasek; David Alan; Vilma Machova; Ales Linhart; Vojtech Novotny; Vladimir Kaucak; Richard Rokyta; Robert Naplava; Zdenek Coufal; Vera Adamkova; Ivo Podpera; Jiri Zizka; Zuzana Motovska; Ivana Marusincova; Premysl Svab; Petr Heinc; Jiri Kuchar; Petr Povolny; Jiri Matuska; Bent Raungaard; Peter Clemmensen; Lia E Bang; Ole May; Morten Bottcher; Jens D Hove; Lars Frost; Gunnar Gislason; John Larsen; Peter Betton Johansen; Flemming Hald; Jorgen Jeppesen; Tonny Nielsen; Kjeld S Kristensen; Piotr Maria Walichiewicz; Jens D Lomholdt; Ib C Klausen; Peter Kaiser Nielsen; Flemming Davidsen; Lars Videbaek; Mai Soots; Veiko Vahula; Anu Hedman; Ullar Soopold; Kaja Martsin; Arved Kristjan; Marja-Riitta Taskinen; Kimmo Porthan; Juhani K Airaksinen; Markus Juonala; Tuomas Kiviniemi; Saila Vikman; Pirjo Posio; Jyrki Taurio; Heikki Huikuri; Kari Kaikkonen; Pierre Coste; Emile Ferrari; Olivier Morel; Gilles Montalescot; Gilles Barone-Rochette; Jacques Mansourati; Yves Cottin; Florence Leclercq; Abdelkader Belhassane; Nicolas Delarche; Franck Boccara; Franck Paganelli; Jerome Clerc; Francois Schiele; Victor Aboyans; Vincent Probst; Jacques Berland; Thierry Lefevre; Bernard Citron; Irakli Khintibidze; Tamaz Shaburishvili; Zurab Pagava; Ramaz Ghlonti; Zaza Lominadze; George Khabeishvili; Rayyan Hemetsberger; Ursula Rauch-Kroehnert; Matthias Stratmann; Karl-Friedrich Appel; Ekkehard Schmidt; Heyder Omran; Christoph Stellbrink; Thomas Dorsel; Emmanouil Lianopoulos; Roger Marx; Andreas Zirlik; Detlev Schellenberg; Thomas Heitzer; Ulrich Laufs; Stephan Gielen; Bernhard Winkelmann; Steffen Behrens; Karsten Sydow; Gregor Simonis; Thomas Muenzel; Nikos Werner; Stefan Leggewie; Dirk Boecker; Ruediger Braun-Dullaeus; Nicole Toursarkissian; Michael Jeserich; Matthias Weissbrodt; Tim Schaeufele; Joachim Weil; Heinz Voeller; Johannes Waltenberger; Mohammed Natour; Susanne Schmitt; Stephan Steiner; Lothar Heidenreich; Uwe Gremmler; Holger Killat; Werner Rieker; Sotiris Patsilinakos; Athanasios Kartalis; Athanassios Manolis; Dimitrios Sionis; Ioannis Skoumas; Vasilios Athyros; Panagiotis Vardas; Frangkiskos Parthenakis; Dimitrios Alexopoulos; Georgios Hahalis; John Lekakis; Apostolos Hatzitolios; Sergio R Fausto Ovando; Juan L Arango Benecke; Edgar R Rodriguez De Leon; Bryan PY Yan; David CW Siu; Tibor Turi; Bela Merkely; Imre Ungi; Geza Lupkovics; Lajos Nagy; Andras Katona; Istvan Edes; Gabor Muller; Ivan Horvath; Tibor Kapin; Jozsef Falukozy; Mukund Kumbla; Manjinder Sandhu; Sharath Annam; Naveen Reddy Proddutur; Rajendra K Premchand; Ajaykumar Mahajan; Atul D Abhyanakar; Prafulla Kerkar; Ravishankar A Govinda; Abraham Oomman; Dhurjati Sinha; Sachin N Patil; Dhiman Kahali; Jitendra Sawhney; Abhijeet B Joshi; Sanjeev Chaudhary; Pankaj Harkut; Santanu Guha; Sanjay Porwal; Srimannarayana Jujjuru; Ramesh B Pothineni; Minguel R Monteiro; Aziz Khan; Shamanna S Iyengar; Jasprakash Singh Grewal; Manoj Chopda; Mahesh C Fulwani; Aparna Patange; Vijay K Chopra; Naresh K Goyal; Rituparna Shinde; Gajendra V Manakshe; Nitin Patki; Sumeet Sethi; Vengatesh Munusamy; Sunil Karna; Srilakshmi Adhyapak; Ulhas Pandurangi; Rishabh Mathur; Suhas Kalashetti; Ajit Bhagwat; Bagirath Raghuraman; Shiv Kumar Yerra; Prasant Bhansali; Rohidas Borse; Srihari Das; Jabir Abdullakutty; Shireesh Saathe; Priya Palimkar; Jabir Abdullkutty; Shireesh Sathe; Shaul Atar; Michael Shechter; Morris Mosseri; Yaron Arbel; Chaim Lotan; Uri Rosenschein; Amos Katz; Yaakov Henkin; Adi Francis; Marc Klutstein; Eugenia Nikolsky; Yoav Turgeman; Majdi Halabi; Ran Kornowski; Michael Jonas; Offer Amir; Yoseph Rozenman; Shmuel Fuchs; Osamah Hussein; Dov Gavish; Zvi Vered; Yoseph Caraco; Mazen Elias; Naveh Tov; Michael Lishner; Nizar Elias; Giancarlo Piovaccari; Annamaria De Pellegrin; Gabriele Guardigli; Giovanni Licciardello; Carla Auguadro; Claudio Cuccia; Alessandro Salvioni; Giuseppe Musumeci; Paolo Calabro; Salvatore Novo; Pompilio Faggiano; Nicoletta B De Cesare; Sergio Berti; Claudio Cavallini; Enrico Puccioni; Marcello Galvani; Maurizio Tespili; Piermarco Piatti; Michela Palvarini; Giuseppe De Luca; Roberto Violini; Alessandro De Leo; Pasquale Perrone Filardi; Maurizio Ferratini; Vittorio Ricca; Kazuoki Dai; Haruo Kamiya; Kenji Ando; Yoshihiro Takeda; Yoshihiro Morino; Yoshiki Hata; Kazuo Kimura; Koichi Kishi; Ichiro Michishita; Hiroki Uehara; Toshinori Higashikata; Atsushi Hirayama; Keiji Hirooka; Satoru Sakagami; Shuichi Taguchi; Akihiro Koike; Hiroyuki Fujinaga; Shinji Koba; Ken Kozuma; Tomohiro Kawasaki; Yujiro Ono; Masatoshi Shimizu; Yousuke Katsuda; Atsuyuki Wada; Toshiro Shinke; Junya Ako; Kenshi Fujii; Toshiyuki Takahashi; Tomohiro Sakamoto; Yutaka Furukawa; Hiroshi Sugino; Toshiaki Mano; Noriaki Utsu; Kashima Ito; Takuya Haraguchi; Yasunori Ueda; Akira Nishibe; Kazuteru Fujimoto; Motomaru Masutani; Jung Han Yoon; Hun Sik Park; In-Ho Chae; Moo Hyun Kim; Myung Ho Jeong; Seungwoon Rha; Chongjin Kim; Hyo-Soo Kim; Taekjong Hong; Seung-Jea Tahk; Youngkwon Kim; Arija Busmane; Natalija Pontaga; Aldis Strelnieks; Iveta Mintale; Iveta Sime; Zaneta Petrulioniene; Roma Kavaliauskiene; Ruta Jurgaitiene; Gintare Sakalyte; Rimvydas Slapikas; Sigute Norkiene; Nerijus Misonis; Aleksandras Kibarskis; Raimondas Kubilius; Stojko Bojovski; Nensi Lozance; Aleksandar Kjovkaroski; Snezana Doncovska; Tiong Kiam Ong; Sazzli Kasim; Oteh Maskon; Balachandran Kandasamy; Houng B Liew; Wan Mohd Izani Wan Mohamed; Armando Garcia Castillo; Jorge Carrillo Calvillo; Pedro Fajardo Campos; Juan Carlos Nunez Fragoso; Edmundo Alfredo Bayram Llamas; Marco Antonio Alcocer Gamba; Jaime Carranza Madrigal; Luis Gerardo Gonzalez Salas; Enrique Lopez Rosas; Belinda Gonzalez Diaz; Eduardo Salcido Vazquez; Alfredo Nacoud Ackar; Guillermo Antonio Llamas Esperon; Carlos Rodolfo Martinez Sanchez; Maria Guerrero De Leon; Rodrigo Suarez Otero; Guillermo Fanghanel Salmon; Jesus Antonio Perez Rios; Jose Angel Garza Ruiz; Robert W Breedveld; Pieter AM Hoogslag; Harry Suryapranata; Antonius Oomen; Jacobijne J Wiersma; Ruud MA Van Der Wal; Pascalle S Hooft Van Huysduynen-Monraats; Ioannis Karalis; Gerardus JE Verdel; Bart RG Brueren; Roland PTh Troquay; Eric P Viergever; Nadea YY Al-Windy; Gerard L Bartels; Jan H Cornel; Walter RM Hermans; Johannes PR Herrman; Robert J Bos; Reginald GEJ Groutars; Coenraad C Van Der Zwaan; Refik Kaplan; Eelko Ronner; Bjorn E Groenemeijer; Patrick NA Bronzwaer; Anho AH Liem; Bernard JWM Rensing; Marcel JJA Bokern; Remco Nijmeijer; Ferry MRJ Hersbach; Frank F Willems; Antonius TM Gosselink; John Elliott; Gerard Wilkins; Raewyn Fisher; Douglas Scott; Hamish Hart; Ralph Stewart; Scott Harding; Ian Ternouth; Nicholas Fisher; Denise Aitken; Russell Anscombe; Laura Davidson; Tadeusz Tomala; Ottar Nygard; Jon Arne Sparby; Kjell Andersen; Lars Gullestad; Jarle Jortveit; Peter S Munk; Erlend Gyllensten Singsaas; Ulf Hurtig; Jorge R Calderon Ticona; Julio R Durand Velasquez; Sandra A Negron Miguel; Enrique S Sanabria Perez; Jesus M Carrion Chambilla; Carlos A Chavez Ayala; Reynaldo P Castillo Leon; Rolando J Vargas Gonzales; Jose D Hernandez Zuniga; Luis A Camacho Cosavalente; Jorge E Bravo Mannucci; Javier Heredia Landeo; Nassip C Llerena Navarro; Yudy M Roldan Concha; V-ctor E Rodriguez Chavez; Henry A Anchante Hernandez; Carlos A Zea Nunez; Walter Mogrovejo Ramos; Arthur Ferrolino; Rosa Allyn G Sy; Louie Tirador; Generoso Matiga; Raul Martin Coching; Alisa Bernan; Gregorio Rogelio; Dante D Morales; Edgar Tan; Dennis Jose Sulit; Adrian Wlodarczak; Krystyna Jaworska; Grzegorz Skonieczny; Lidia Pawlowicz; Pawel Wojewod; Benita Busz-Papiez; Janusz Bednarski; Aleksander Goch; Pawel Staneta; Elzbieta Dulak; Krzysztof Saminsk; Wlodzimierz Krasowski; Wanda Sudnik; Aleksander Zurakowski; Marcin Skorski; Roman Lysek; Beata Miklaszewicz; Jacek Kubica; Jan Andrzej Lipko; Edyta Kostarska-Srokosz; Marek Piepiorka; Anna Drzewiecka; Ryszard Sciborski; Arkadiusz Stasiewski; Tomasz Blicharski; Leszek Bystryk; Michal Szpajer; Marek Korol; Tomasz Czerski; Ewa Mirek-Bryniarska; Jacek Gniot; Andrzej Lubinski; Jerzy Gorny; Edward Franek; Grzegorz Raczak; Hanna Szwed; Pedro Monteiro; Jose Mesquita Bastos; Helder H Pereira; Dinis Martins; Filipe Seixo; Carlos Mendonca; Ana Botelho; Bogdan Minescu; Octavian Istratoaie; Dan N Tesloianu; Gabriel Cristian; Cristian GC Podoleanu; Mircea CA Constantinescu; Cristina M Bengus; Constantin Militaru; Doina Rosu; Irinel R Parepa; Adrian V Matei; Tom M Alexandru; Ioan Coman; Rodica Stanescu Cioranu; Doina Dimulescu; Yury Shvarts; Olga Orlikova; Zhanna Kobalava; Olga L Barbarash; Valentin Markov; Nadezhda Lyamina; Alexander Gordienko; Konstantin Zrazhevsky; Alexander Y Vishnevsky; Victor Gurevich; Raisa Stryuk; Nikita V Lomakin; Igor Bokarev; Sergey Shalaev; Larisa Khaisheva; Petr Chizhov; Inna Viktorova; Natalya Osokina; Evgenia Akatova; Galina Chumakova; Igor Libov; Mikhail I Voevoda; Tatyana V Tretyakova; Evgeny Baranov; Sergey Shustov; Sergey Yakushin; Ivan Gordeev; Niiaz Khasanov; Olga Reshetko; Tatiana Sotnikova; Olga Molchanova; Konstantin Nikolaev; Liudmila Gapon; Elena Baranova; Zaur Shogenov; Elena Kosmachova; Yuriy Karpov; Anton Povzun; Liudmila Egorova; Vadim V Tyrenko; Igor G Ivanov; Sergey Kanorsky; Dragan Simic; Nikola Ivanovic; Goran Davidovic; Nebojsa Tasic; Milika R Asanin; Stevo Stojic; Svetlana R Apostolovic; Stevan Ilic; Biljana Putnikovic; Aleksandar Stankovic; Aleksandra Arandjelovic; Slavica Radovanovic; Jovan Balinovac; Dragan V Dincic; Petar Seferovic; Slobodan Dodic; Sinisa Dimkovic; Kian-Keong Poh; Hean Yee Ong; Karol Micko; Jan Nociar; Daniel Pella; Peter Fulop; Marian Hranai; Juraj Palka; Juraj Mazur; Ivan Majercak; Andrej Dzupina; Frantisek Fazekas; Jozef Gonsorcik; Viliam Bugan; Juraj Selecky; Gabriel Kamensky; Jaroslava Strbova; Rudolf Smik; Andrej Dukat; Peter Olexa; Ivan Zuran; Janez Poklukar; Natasa Cerni Suligoj; Matija Cevc; Henry P Cyster; Naresh Ranjith; Clive Corbett; Junaid Bayat; Ellen Makoali Makotoko; Ilse E Kapp; Matthys M de V Basson; Hanlie Lottering; Louis J Van Zyl; Peter J Sebastian; Thayabran Pillay; Jan A Saaiman; Patrick J Commerford; Soraya Cassimjee; Iftikhar O Ebrahim; Mahomed Sarvan; Joseph H Mynhardt; Helmuth Reuter; Rajendran Moodley; Manuel Vida; Angel R Cequier Fillat; Vicente Bodi Peris; Francisco Fuentes Jimenez; Francisco Marin; Jose M Cruz Fernandez; Blas Gil-Extremera; Fernando Worner Diz; David Garcia-Dorado; Andres Iniguez; Jose Tunon Fernandez; Jose R Gonzalez-Juanatey; Javier Fernandez Portales; Fernando Civeira Murillo; Laia Matas Pericas; Jose Luis Zamorano; Manuel De Mora Martin; Jordi Bruguera Cortada; Joaquin J Alonso Martin; Jose R De Berrazueta Fernandez; Jose Francisco Diaz Fernandez; Jose Alberto Garcia Lledo; Juan Cosin Sales; Javier Botas Rodriguez; Gabriel Gusi Tragant; Amparo Benedicto; Carlos Gonzalez-Juanatey; Mercedes Camprubi Potau; Ignacio Plaza Perez; Cesar Moris De La Tassa; Pablo Loma-Osorio Rincon; Javier Balaguer Recena; Juan M Escudier; Antonio Coca Payeras; Norberto Alonso Orcajo; Pedro Valdivielso; Godwin Constantine; Ruvaiz Haniffa; Nirmali Tissera; Stanley Amarasekera; Nimali Fernando; Jayanthimala Jayawardena; Wijeyasingam Santharaj; Ruvan Ekanayaka; Sepalika Mendis; Vajira Senaratne; Gnanamoorthy Mayurathan; Thilak Sirisena; Ajantha Rajapaksha; Jagath I Herath; Naomali Amarasena; Stefan Berglund; Gundars Rasmanis; Nils Witt; Georgios Mourtzinis; Peter Nicol; Ole Hansen; Stefano Romeo; Steen Agergaard Jensen; Ingemar Torstensson; Ulf Ahremark; Torbjorn Sundelin; Tiziano Moccetti; Francois Mach; Ronald Binder; Wei-Chuan Tsai; Kwo-Chang Ueng; Wen-Ter Lai; Ming-En Liu; Juey-Jen Hwang; Wei-Hsian Yin; I-Chang Hsieh; Wei Hsiang Lin; Jen-Yuan Kuo; Tsuei-Yuan Huang; Chih-Yuan Fang; Pinij Kaewsuwanna; Wasant Soonfuang; Woravut Jintapakorn; Apichard Sukonthasarn; Nattawut Wongpraparut; Krisada Sastravaha; Nakarin Sansanayudh; Wirash Kehasukcharoen; Dilok Piyayotai; Paiboon Chotnoparatpat; Ahmet Camsari; Hakan Kultursay; Bulent Mutlu; Murat Ersanli; Mustafa Demirtas; Cevat Kirma; Ertan Ural; Lale Koldas; Oleksandr Karpenko; Alexander Prokhorov; Ihor Vakaluyk; Halyna Myshanych; Dmytro Reshotko; Valeriy Batushkin; Leonid Rudenko; Ihor Kovalskyi; Mykola Kushnir; Vira Tseluyko; Yuriy Mostovoy; Mykola Stanislavchuk; Yulian Kyiak; Yuriy Karpenko; Yaroslav Malynovsky; Andriy Klantsa; Oles Kutniy; Ekaterina Amosova; Viktor Tashchuk; Oleh Leshchuk; Mykola Rishko; Mykola Kopytsya; Andriy Yagensky; Mykola Vatutin; Andriy Bagriy; Olga M Barna; Olexiy Ushakov; Georgiy Dzyak; Borys Goloborodko; Anatolii Rudenko; Volodymyr Zheleznyy; Jasper Trevelyan; Azfar Zaman; Kaeng Lee; Andrew Moriarty; Rajesh K Aggarwal; Piers Clifford; Yuk-Ki Wong; Syed MR Iqbal; Eduardas Subkovas; 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doi:10.1016/j.jacc.2019.03.013

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Alirocumab in Patients With Polyvascular Disease and Recent Acute Coronary Syndrome ODYSSEY OUTCOMES Trial

Journal article

Open access

Peer reviewed

Alirocumab in Patients With Polyvascular Disease and Recent Acute Coronary Syndrome ODYSSEY OUTCOMES Trial

J Wouter Jukema, Michael Szarek, Laurien E Zijlstra, H Asita de Silva, Deepak L Bhatt, Vera A Bittner, Rafael Diaz, Jay M Edelberg, Shaun G Goodman, Corinne Hanotin, …

09/03/2019

DOI: https://doi.org/10.1016/j.jacc.2019.03.013

Abstract

acute coronary syndrome

alirocumab

ARTERY-DISEASE

Cardiac & Cardiovascular Systems

CARDIOVASCULAR EVENT RATES

Cardiovascular System & Cardiology

cerebrovascular disease

CHOLESTEROL

death

INSIGHTS

Life Sciences & Biomedicine

major adverse cardiac events

MANAGEMENT

OUTPATIENTS

PCSK9 INHIBITION

peripheral artery disease

RISK

Science & Technology

BACKGROUND: Patients with acute coronary syndrome (ACS) and concomitant noncoronary atherosclerosis have a high risk of major adverse cardiovascular events (MACEs) and death. The impact of lipid lowering by proprotein convertase subtilisin-kexin type 9 inhibition in such patients is undetermined. OBJECTIVES: This pre-specified analysis from ODYSSEY OUTCOMES (Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab) determined whether polyvascular disease influenced risks of MACEs and death and their modification by alirocumab in patients with recent ACS and dyslipidemia despite intensive statin therapy. METHODS: Patients were randomized to alirocumab or placebo 1 to 12 months after ACS. The primary MACEs endpoint was the composite of coronary heart disease death, nonfatal myocardial infarction, fatal or nonfatal ischemic stroke, or unstable angina requiring hospitalization. All-cause death was a secondary endpoint. RESULTS: Median follow-up was 2.8 years. Of 18,924 patients, 17,370 had monovascular (coronary) disease, 1,405 had polyvascular disease in 2 beds (coronary and peripheral artery or cerebrovascular), and 149 had polyvascular disease in 3 beds (coronary, peripheral artery, cerebrovascular). With placebo, the incidence of MACEs by respective vascular categories was 10.0%, 22.2%, and 39.7%. With alirocumab, the corresponding absolute risk reduction was 1.4% (95% confidence interval [CI]: 0.6% to 2.3%), 1.9% (95% CI: -2.4% to 6.2%), and 13.0% (95% CI: -2.0% to 28.0%). With placebo, the incidence of death by respective vascular categories was 3.5%, 10.0%, and 21.8%; the absolute risk reduction with alirocumab was 0.4% (95% CI: -0.1% to 1.0%), 1.3% (95% CI: -1.8% to 4.3%), and 16.2% (95% CI: 5.5% to 26.8%). CONCLUSIONS: In patients with recent ACS and dyslipidemia despite intensive statin therapy, polyvascular disease is associated with high risks of MACEs and death. The large absolute reductions in those risks with alirocumab are a potential benefit for these patients. (Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab [ODYSSEY OUTCOMES]: NCT01663402). status: published

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Title: Alirocumab in Patients With Polyvascular Disease and Recent Acute Coronary Syndrome ODYSSEY OUTCOMES Trial
Creators: J Wouter Jukema - Leiden University Medical Center
Michael Szarek - SUNY Downstate Medical Center
Laurien E Zijlstra - Leiden University Medical Center
H Asita de Silva
Deepak L Bhatt - Brigham and Women's Hospital
Vera A Bittner - University of Alabama at Birmingham
Rafael Diaz - Instituto Cardiovascular de Rosario
Jay M Edelberg - Sanofi
Shaun G Goodman - University of Alberta
Corinne Hanotin - Sanofi
Robert A Harrington - Center for Clinical Research
Yuri Karpov - Russian Cardiological Scientific-Productive Complex, Moscow, Russian Federation.
Angle Moryusef
Robert Pordy - Regeneron
Juan C Prieto - University of Chile
Matthew T Roe - Duke University
Harvey D White - Auckland City Hospital
Andreas M Zeiher - Goethe University Frankfurt
Gregory G Schwartz - University of Colorado Denver
P Gabriel Steg - National Institutes of Health
Pierluigi Tricoci
Kenneth W Mahaffey
Guillaume Lecorps
Angele Moryusef - Sanofi
William J Sasiela
Jean-Francois Tamby
Philip E Aylward
Heinz Drexel
Peter Sinnaeve
Mirza Dilic
Nina N Gotcheva
Juan-Carlos Prieto - University of Chile
Huo Yong
Patricio Lopez-Jaramillo
Ivan Pecin
Zeljko Reiner
Petr Ostadal
Steen Hvitfeldt Poulsen
Margus Viigimaa
Markku S Nieminen
Nicolas Danchin
Vakhtang Chumburidze
Nikolaus Marx
Evangelos Liberopoulos
Pablo Carlos Montenegro Valdovinos
Hung-Fat Tse
Robert Gabor Kiss
Denis Xavier
Doron Zahger
Marco Valgimigli
Takeshi Kimura
Hyo Soo Kim
Sang-Hyun Kim
Sasko Kedev
Andrejs Erglis
Aleksandras Laucevicius
Khalid Yusoff
Ramos Lopez
Gabriel Arturo Ramos Lopez
Marco Alings
Sigrun Halvorsen
Roger M Correa Flores
Rody G Sy
Andrzej Budaj
Joao Morais
Maria Dorobantu
Arsen D Ristic
Terrance Chua
Jan Murin
Zlatko Fras
Anthony J Dalby
Jose Tunon
Emil Hagstrom
Christian Muller
Chern-En Chiang
Piyamitr Sritara
Sema Guneri
Alexander Parkhomenko
Kausik K Ray
Patrick M Moriarty
Bernard Chaitman
Sheryl F Kelsey
Anders G Olsson
Jean-Lucien Rouleau
Maarten L Simoons
Karen Alexander
Chiara Meloni
Robert Rosenson
Eric JG Sijbrands
John H Alexander
Luciana Armaganijan
Akshay Bagai
Maria Cecilia Bahit
J Matthew Brennan
Shaun Clifton
Adam D DeVore
Shalonda Deloatch
Sheila Dickey
Keith Dombrowski
Gregory Ducrocq
Zubin Eapen
Patricia Endsley
Arleen Eppinger
Robert W Harrison
Connie Ng Hess
Mark A Hlatky
Joseph Dedrick Jordan
Joshua W Knowles
Bradley J Kolls
David F Kong
Sergio Leonardi
Linda Lillis
David J Maron
Jill Marcus
Robin Mathews
Rajendra H Mehta
Robert J Mentz
Humberto Graner Moreira
Chetan B Patel
Sabrina Bernardez Pereira
Lynn Perkins
Thomas J Povsic
Etienne Puymirat
William Schuyler Jones
Bimal R Shah
Matthew W Sherwood
Kenya Stringfellow
Darin Sujjavanich
Mustafa Toma
Sean FP Van Diepen
Matthew D Wilson
Andrew Tze-Kay Yan
Renato D Lopes
Charlene Trotter
Lilia B Schiavi
Marcelo Garrido
Andres F Alvarisqueta
Sonia A Sassone
Anselmo P Bordonava
Alberto E Alves De Lima
Jorge M Schmidberg
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Leonardo P Novaretto
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Gregory Starmer
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Ronald Dick
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Dirk Faes
Kurt Hermans
Bruno Pirenne
Attilio Leone
Etienne Hoffer
Mathias CM Vrolix
Luc De Wolf
Bart Wollaert
Marc Castadot
Karl Dujardin
Christophe Beauloye
Geert Vervoort
Harry Striekwold
Carl Convens
John Roosen
Emanuele Barbato
Marc Claeys
Frank Cools
Ibrahim Terzic
Fahir Barakovic
Zlatko Midzic
Belma Pojskic
Emir Fazlibegovic
Azra Durak-Nalbantic
Dusko Vulic
Adis Muslibegovic
Boris Goronja
Gilmar Reis
Luciano Sousa
Jose C Nicolau
Flavio E Giorgeto
Ricardo P Silva
Lilia Nigro Maia
Rafael Rech
Paulo RF Rossi
Maria Jose AG Cerqueira
Norberto Duda
Renato Kalil
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Jose Antonio M Abrantes
Pedro Pimentel Filho
Ana Priscila Soggia
Mayler ON de Santos
Fernando Neuenschwander
Luiz C Bodanese
Yorghos L Michalaros
Freddy G Eliaschewitz
Maria H Vidotti
Paulo E Leaes
Roberto V Botelho
Sergio Kaiser
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Dalton B Precoma
Jose C Moura Jorge
Pedro GM de B Silva
Jose A Silveira
Wladmir Saporito
Jose A Marin Neto
Gilson S Feitosa
Luiz Eduardo F Ritt
Juliana A de Souza
Fernando Costa
Weimar KSB Souza
Helder JL Reis
Leandro Machado
Jose Carlos Aidar Ayoub
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Fedya P Nikolov
Elena S Velcheva
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James Stone
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Simon Kouz
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Serge Lepage
Shamir Mehta
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Hussein Fadlallah
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Monica Acevedo
Arnoldo Aguirre
Margarita Vejar
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Lan Huang
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Guohai Su
Biao Xu
Xi Su
Xiaoshu Cheng
Jinxiu Lin
Wenxia Zong
Huanming Li
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Yuannan Ke
Xuefeng Lin
Zheng Zhang
Zeqi Zheng
Zhurong Luo
Yundai Chen
Chunhua Ding
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Xiaodong Li
Daoquan Peng
Ying Li
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Yihua Yu
Baiming Qu
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Jian'An Wang
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Vera Adamkova
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Ajit Bhagwat
Bagirath Raghuraman
Shiv Kumar Yerra
Prasant Bhansali
Rohidas Borse
Srihari Das
Jabir Abdullakutty
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Priya Palimkar
Jabir Abdullkutty
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Michael Shechter
Morris Mosseri
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Uri Rosenschein
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Yaakov Henkin
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Marc Klutstein
Eugenia Nikolsky
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Yoseph Rozenman
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Kazuo Kimura
Koichi Kishi
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Hiroki Uehara
Toshinori Higashikata
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Keiji Hirooka
Satoru Sakagami
Shuichi Taguchi
Akihiro Koike
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Junya Ako
Kenshi Fujii
Toshiyuki Takahashi
Tomohiro Sakamoto
Yutaka Furukawa
Hiroshi Sugino
Toshiaki Mano
Noriaki Utsu
Kashima Ito
Takuya Haraguchi
Yasunori Ueda
Akira Nishibe
Kazuteru Fujimoto
Motomaru Masutani
Jung Han Yoon
Hun Sik Park
In-Ho Chae
Moo Hyun Kim
Myung Ho Jeong
Seungwoon Rha
Chongjin Kim
Hyo-Soo Kim
Taekjong Hong
Seung-Jea Tahk
Youngkwon Kim
Arija Busmane
Natalija Pontaga
Aldis Strelnieks
Iveta Mintale
Iveta Sime
Zaneta Petrulioniene
Roma Kavaliauskiene
Ruta Jurgaitiene
Gintare Sakalyte
Rimvydas Slapikas
Sigute Norkiene
Nerijus Misonis
Aleksandras Kibarskis
Raimondas Kubilius
Stojko Bojovski
Nensi Lozance
Aleksandar Kjovkaroski
Snezana Doncovska
Tiong Kiam Ong
Sazzli Kasim
Oteh Maskon
Balachandran Kandasamy
Houng B Liew
Wan Mohd Izani Wan Mohamed
Armando Garcia Castillo
Jorge Carrillo Calvillo
Pedro Fajardo Campos
Juan Carlos Nunez Fragoso
Edmundo Alfredo Bayram Llamas
Marco Antonio Alcocer Gamba
Jaime Carranza Madrigal
Luis Gerardo Gonzalez Salas
Enrique Lopez Rosas
Belinda Gonzalez Diaz
Eduardo Salcido Vazquez
Alfredo Nacoud Ackar
Guillermo Antonio Llamas Esperon
Carlos Rodolfo Martinez Sanchez
Maria Guerrero De Leon
Rodrigo Suarez Otero
Guillermo Fanghanel Salmon
Jesus Antonio Perez Rios
Jose Angel Garza Ruiz
Robert W Breedveld
Pieter AM Hoogslag
Harry Suryapranata
Antonius Oomen
Jacobijne J Wiersma
Ruud MA Van Der Wal
Pascalle S Hooft Van Huysduynen-Monraats
Ioannis Karalis
Gerardus JE Verdel
Bart RG Brueren
Roland PTh Troquay
Eric P Viergever
Nadea YY Al-Windy
Gerard L Bartels
Jan H Cornel
Walter RM Hermans
Johannes PR Herrman
Robert J Bos
Reginald GEJ Groutars
Coenraad C Van Der Zwaan
Refik Kaplan
Eelko Ronner
Bjorn E Groenemeijer
Patrick NA Bronzwaer
Anho AH Liem
Bernard JWM Rensing
Marcel JJA Bokern
Remco Nijmeijer
Ferry MRJ Hersbach
Frank F Willems
Antonius TM Gosselink
John Elliott
Gerard Wilkins
Raewyn Fisher
Douglas Scott
Hamish Hart
Ralph Stewart
Scott Harding
Ian Ternouth
Nicholas Fisher
Denise Aitken
Russell Anscombe
Laura Davidson
Tadeusz Tomala
Ottar Nygard
Jon Arne Sparby
Kjell Andersen
Lars Gullestad
Jarle Jortveit
Peter S Munk
Erlend Gyllensten Singsaas
Ulf Hurtig
Jorge R Calderon Ticona
Julio R Durand Velasquez
Sandra A Negron Miguel
Enrique S Sanabria Perez
Jesus M Carrion Chambilla
Carlos A Chavez Ayala
Reynaldo P Castillo Leon
Rolando J Vargas Gonzales
Jose D Hernandez Zuniga
Luis A Camacho Cosavalente
Jorge E Bravo Mannucci
Javier Heredia Landeo
Nassip C Llerena Navarro
Yudy M Roldan Concha
V-ctor E Rodriguez Chavez
Henry A Anchante Hernandez
Carlos A Zea Nunez
Walter Mogrovejo Ramos
Arthur Ferrolino
Rosa Allyn G Sy
Louie Tirador
Generoso Matiga
Raul Martin Coching
Alisa Bernan
Gregorio Rogelio
Dante D Morales
Edgar Tan
Dennis Jose Sulit
Adrian Wlodarczak
Krystyna Jaworska
Grzegorz Skonieczny
Lidia Pawlowicz
Pawel Wojewod
Benita Busz-Papiez
Janusz Bednarski
Aleksander Goch
Pawel Staneta
Elzbieta Dulak
Krzysztof Saminsk
Wlodzimierz Krasowski
Wanda Sudnik
Aleksander Zurakowski
Marcin Skorski
Roman Lysek
Beata Miklaszewicz
Jacek Kubica
Jan Andrzej Lipko
Edyta Kostarska-Srokosz
Marek Piepiorka
Anna Drzewiecka
Ryszard Sciborski
Arkadiusz Stasiewski
Tomasz Blicharski
Leszek Bystryk
Michal Szpajer
Marek Korol
Tomasz Czerski
Ewa Mirek-Bryniarska
Jacek Gniot
Andrzej Lubinski
Jerzy Gorny
Edward Franek
Grzegorz Raczak
Hanna Szwed
Pedro Monteiro
Jose Mesquita Bastos
Helder H Pereira
Dinis Martins
Filipe Seixo
Carlos Mendonca
Ana Botelho
Bogdan Minescu
Octavian Istratoaie
Dan N Tesloianu
Gabriel Cristian
Cristian GC Podoleanu
Mircea CA Constantinescu
Cristina M Bengus
Constantin Militaru
Doina Rosu
Irinel R Parepa
Adrian V Matei
Tom M Alexandru
Ioan Coman
Rodica Stanescu Cioranu
Doina Dimulescu
Yury Shvarts
Olga Orlikova
Zhanna Kobalava
Olga L Barbarash
Valentin Markov
Nadezhda Lyamina
Alexander Gordienko
Konstantin Zrazhevsky
Alexander Y Vishnevsky
Victor Gurevich
Raisa Stryuk
Nikita V Lomakin
Igor Bokarev
Sergey Shalaev
Larisa Khaisheva
Petr Chizhov
Inna Viktorova
Natalya Osokina
Evgenia Akatova
Galina Chumakova
Igor Libov
Mikhail I Voevoda
Tatyana V Tretyakova
Evgeny Baranov
Sergey Shustov
Sergey Yakushin
Ivan Gordeev
Niiaz Khasanov
Olga Reshetko
Tatiana Sotnikova
Olga Molchanova
Konstantin Nikolaev
Liudmila Gapon
Elena Baranova
Zaur Shogenov
Elena Kosmachova
Yuriy Karpov
Anton Povzun
Liudmila Egorova
Vadim V Tyrenko
Igor G Ivanov
Sergey Kanorsky
Dragan Simic
Nikola Ivanovic
Goran Davidovic
Nebojsa Tasic
Milika R Asanin
Stevo Stojic
Svetlana R Apostolovic
Stevan Ilic
Biljana Putnikovic
Aleksandar Stankovic
Aleksandra Arandjelovic
Slavica Radovanovic
Jovan Balinovac
Dragan V Dincic
Petar Seferovic
Slobodan Dodic
Sinisa Dimkovic
Kian-Keong Poh
Hean Yee Ong
Karol Micko
Jan Nociar
Daniel Pella
Peter Fulop
Marian Hranai
Juraj Palka
Juraj Mazur
Ivan Majercak
Andrej Dzupina
Frantisek Fazekas
Jozef Gonsorcik
Viliam Bugan
Juraj Selecky
Gabriel Kamensky
Jaroslava Strbova
Rudolf Smik
Andrej Dukat
Peter Olexa
Ivan Zuran
Janez Poklukar
Natasa Cerni Suligoj
Matija Cevc
Henry P Cyster
Naresh Ranjith
Clive Corbett
Junaid Bayat
Ellen Makoali Makotoko
Ilse E Kapp
Matthys M de V Basson
Hanlie Lottering
Louis J Van Zyl
Peter J Sebastian
Thayabran Pillay
Jan A Saaiman
Patrick J Commerford
Soraya Cassimjee
Iftikhar O Ebrahim
Mahomed Sarvan
Joseph H Mynhardt
Helmuth Reuter
Rajendran Moodley
Manuel Vida
Angel R Cequier Fillat
Vicente Bodi Peris
Francisco Fuentes Jimenez
Francisco Marin
Jose M Cruz Fernandez
Blas Gil-Extremera
Fernando Worner Diz
David Garcia-Dorado
Andres Iniguez
Jose Tunon Fernandez
Jose R Gonzalez-Juanatey
Javier Fernandez Portales
Fernando Civeira Murillo
Laia Matas Pericas
Jose Luis Zamorano
Manuel De Mora Martin
Jordi Bruguera Cortada
Joaquin J Alonso Martin
Jose R De Berrazueta Fernandez
Jose Francisco Diaz Fernandez
Jose Alberto Garcia Lledo
Juan Cosin Sales
Javier Botas Rodriguez
Gabriel Gusi Tragant
Amparo Benedicto
Carlos Gonzalez-Juanatey
Mercedes Camprubi Potau
Ignacio Plaza Perez
Cesar Moris De La Tassa
Pablo Loma-Osorio Rincon
Javier Balaguer Recena
Juan M Escudier
Antonio Coca Payeras
Norberto Alonso Orcajo
Pedro Valdivielso
Godwin Constantine
Ruvaiz Haniffa
Nirmali Tissera
Stanley Amarasekera
Nimali Fernando
Jayanthimala Jayawardena
Wijeyasingam Santharaj
Ruvan Ekanayaka
Sepalika Mendis
Vajira Senaratne
Gnanamoorthy Mayurathan
Thilak Sirisena
Ajantha Rajapaksha
Jagath I Herath
Naomali Amarasena
Stefan Berglund
Gundars Rasmanis
Nils Witt
Georgios Mourtzinis
Peter Nicol
Ole Hansen
Stefano Romeo
Steen Agergaard Jensen
Ingemar Torstensson
Ulf Ahremark
Torbjorn Sundelin
Tiziano Moccetti
Francois Mach
Ronald Binder
Wei-Chuan Tsai
Kwo-Chang Ueng
Wen-Ter Lai
Ming-En Liu
Juey-Jen Hwang
Wei-Hsian Yin
I-Chang Hsieh
Wei Hsiang Lin
Jen-Yuan Kuo
Tsuei-Yuan Huang
Chih-Yuan Fang
Pinij Kaewsuwanna
Wasant Soonfuang
Woravut Jintapakorn
Apichard Sukonthasarn
Nattawut Wongpraparut
Krisada Sastravaha
Nakarin Sansanayudh
Wirash Kehasukcharoen
Dilok Piyayotai
Paiboon Chotnoparatpat
Ahmet Camsari
Hakan Kultursay
Bulent Mutlu
Murat Ersanli
Mustafa Demirtas
Cevat Kirma
Ertan Ural
Lale Koldas
Oleksandr Karpenko
Alexander Prokhorov
Ihor Vakaluyk
Halyna Myshanych
Dmytro Reshotko
Valeriy Batushkin
Leonid Rudenko
Ihor Kovalskyi
Mykola Kushnir
Vira Tseluyko
Yuriy Mostovoy
Mykola Stanislavchuk
Yulian Kyiak
Yuriy Karpenko
Yaroslav Malynovsky
Andriy Klantsa
Oles Kutniy
Ekaterina Amosova
Viktor Tashchuk
Oleh Leshchuk
Mykola Rishko
Mykola Kopytsya
Andriy Yagensky
Mykola Vatutin
Andriy Bagriy
Olga M Barna
Olexiy Ushakov
Georgiy Dzyak
Borys Goloborodko
Anatolii Rudenko
Volodymyr Zheleznyy
Jasper Trevelyan
Azfar Zaman
Kaeng Lee
Andrew Moriarty
Rajesh K Aggarwal
Piers Clifford
Yuk-Ki Wong
Syed MR Iqbal
Eduardas Subkovas
Denise Braganza
David Sarkar
Robert Storey
Huw Griffiths
Sam Mcclure
Rangasamy Muthusamy
John Kurian
Terry Levy
Craig Barr
Honer Kadr
Robert Gerber
Audrius Simaitis
Handrean Soran
Anthony Mathur
Adrian Brodison
Richard Oliver
Telal Mudawi
Timothy Reynolds
David Sharman
Rob Butler
Peter Wilkinson
Gregory YH Lip
Julian Halcox
Gil Vardi
Duccio Baldari
David Brabham
Charles Treasure
Charles Dahl
Bruce Palmer
Alan Wiseman
Abul Khan
Sanjeev Puri
Ann Elizabeth Mohart
Carlos Ince
Enrique Flores
Scott Wright
Shi-Chi Cheng
Michael Rosenberg
William Rogers
Edward Kosinski
Les Forgosh
Jonathan Waltman
Misal Khan
Mohammad Shoukfeh
Georges Dagher
Ira Lieber
Priya Kumar
Cara East
Perry Krichmar
Lindsey White
Thomas Knickelbine
Thomas Haldis
Eve Gillespie
David Suh
Imran Arif
Faiq Akhter
Eric Carlson
Michael D'Urso
Fadi El-Ahdab
William Nelson
Barry Harris
Steven Cohen
Luther Carter
Kenneth Sabatino
Tariq Haddad
Amir Malik
Sunder Rao
Angel Mulkay
Ion Jovin
Kim Klancke
Vinay Malhotra
Sai K Devarapalli
Michael Koren
Harish Chandna
George Dodds
Matthew Janik
Joseph Moran
Andrew Sumner
John Kobayashi
William Davis
Shahram Yazdani
John Pasquini
Maitreya Thakkar
Amarnath Vedere
Wayne Leimbach
James Rider
Narendra Singh
Anil V Shah
Denise Janosik
Carl Pepine
Brett Berman
Joseph Gelormini
Christopher Daniels
Friederike Keating
Nicholas I Kondo
Sanjay Shetty
Winfried Waider
Theodore Takata
Mazen Abu-Fadel
Vipul Shah
Rahul Aggarwal
Mark Izzo
Anil Kumar
Brack Hattler
Chad Link
Anna Bortnick
George Kinzfogl
Arnold Ghitis
John Larry
Edward Teufel
Peter Kuhlman
Brent Mclaurin
Wenwu Zhang
Stephen Thew
Jalal Abbas
Matthew White
Nandkishore Ranadive
Christian Gring
David Henderson
Timothy Schuchard
Naim Farhat
Geoffrey Kline
Sharan Mahal
Jack Whitaker
Shawn Speirs
Rolf Andersen
Nizar Daboul
Phillip Horwitz
George Ponce
Zubair Jafar
Joseph Mcgarvey
Vipul Panchal
Stephen Voyce
Thomas Blok
William Sheldon
Masoud M Azizad
Carsten Schmalfuss
Mark Picone
William Herzog
Jason Lindsey
Rosemary Nowins
Norman Lepor
Mahfouz El Shahawy
Howard Weintraub
Anand Irimpen
Wade May
Thomas Galski
Alan Chu
Freny Mody
Zachary Hodes
Gregory Rose
James Fairlamb
Charles Lambert
Ajit Raisinghani
Antonio Abbate
Marilyn King
Charles Carey
Jaime Gerber
Liwa Younis
Hyeun Tom Park
Mladen Vidovich
Thomas Knutson
Dennis Friedman
Fred Chaleff
Arthur Loussararian
Phillip Rozeman
Carey Kimmelstiel
Kevin Silver
Malcolm Foster
Glen Tonnessen
Mohamadali Amlani
Andreas Wali
Christopher Malozzi
Keattiyoat Wattanakit
Philip J O'Donnell
Dinesh Singal
Naseem Jaffrani
Sridhar Banuru
Daniel Fisher
Mark Xenakis
Neal Perlmutter
Ravi Bhagwat
James Strader
Ayim Akyea-Djamson
Ajay Labroo
Kwan Lee
H John Marais
Edmund Claxton
Martin Berk
Peter Rossi
Parag Joshi
Ajit S Khaira
Greg Kumkumian
Steven Lupovitch
Joshua Purow
Stephen Welka
David Hoffman
Stuart Fischer
Eugene Soroka
Donald Eagerton
Samir Pancholy
Michael Ray
Michael Farrar
Stewart Pollock
William J French
Steve Diamantis
Lawrence Gimple
Mark Neustel
Steven Schwartz
Edward Pereira
Douglas Spriggs
Janet Strain
Anthony Vo
Majed Chane
Jason Hall
Nampalli Vijay
Kapildeo Lotun
F Martin Lester
Ahed Nahhas
Theodore Pope
Paul Nager
Rakesh Vohra
Riyaz Bashir
Hinan Ahmed
Michael Berlowitz
Robert Fishberg
Robert Barrucco
Eric Yang
Michael Radin
Daniel Sporn
Steven Eisenberg
Joel Landzberg
Martin Mcgough
Samir Turk
Michael Schwartz
P Sandy Sundram
Diwakar Jain
Mark Zainea
Carlos Bayron
Ronald Karlsberg
Henry Lui
William Keen
Donald Westerhausen
Sandeep Khurana
Himanshu Agarwal
Jessica Birchem
William Penny
Mark Chang
Sherrill Murphy
Branislav Schifferdecker
John M Gilbert
Gopal Chalavarya
Charles Eaton
John F Schmedtje
Stuart Christenson
Douglas Denham
Alexander Macdonell
Paul Gibson
Aref Rahman
Tammam Al Joundi
Gary Conrad
Purushotham Kotha
Michael Love
Gregory Giesler
Howard Rubenstein
Laura Akright
Justine Krawczyk
Terry Wells
James Welker
Robert Foster
Richard Gilmore
Jay Anderson
Douglas Jacoby
Bill Harris
Geraldine Gardner
Ramprasad Dandillaya
Kishor Vora
John Kostis
John Hunter
David Laxson
Eric Ball
Alan Camp
Renato Lopes
Flavia Egydio
Anelise Kawakami
Janaina Oliveira
Julianna Wozniak
Alexander Matthews
Caroline Ratky
Janine Valiris
Lisa Berdan
Anita Hepditch
Kirby Quintero
Tyrus Rorick
Melissa Westbrook
Andrea Pascual
Carla Rovito
Madeleine Bezault
Elodie Drouet
Tabassome Simon
Caroline Alsweiler
Anne Luyten
Phil Aylward
Julie Butters
Liddy Griffith
Michelle Shaw
Lena Grunberg
Shahidul Islam
Marie-France Bregeault
Nathalie Bougon
Douglas Faustino
Sylvie Fontecave
Judith Murphy
Melanie Verrier
Veronique Agnetti
Dorthe Andersen
Emmy Badreddine
Mhamed Bekkouche
Cecile Bouancheau
Imane Brigui
Maddy Brocklehurst
Joseph Cianciarulo
Dawn Devaul
Szilvia Domokos
Cecile Gache
Caroline Gobillot
Severine Guillou
Jan Healy
Megan Heath
Gayatri Jaiwal
Carine Javierre
Julien Labeirie
Myriam Monier
Ulises Morales
Asmaa Mrabti
Bicky Mthombeni
Betim Okan
Lucile Smith
Jennifer Sheller
Sebastien Sopena
Valerie Pellan
Fadela Benbernou
Nafissa Bengrait
Maud Lamoureux
Katarina Kralova
Michel Scemama
Raphael Bejuit
Anthony Coulange
Christelle Berthou
Jerome Repincay
Christelle Lorenzato
Alexis Etienne
Valerie Gouet
Virginie Loizeau
Mickael Normand
Anne Ourliac
Christelle Rondel
Antony Adamo
Pascale Beltran
Pauline Barraud
Helene Dubois-Gache
Benjamin Halle
Lamia Metwally
Maxime Mourgues
Marc Sotty
Marion Vincendet
Raluca Cotruta
Chengyue Zhu
Dominique Fournie-Lloret
Christine Morrello
Aurelie Perthuis
Patrick Picault
Isabelle Zobouyan
Publisher: ELSEVIER SCIENCE INC
Identifiers: 991005956166502656
Academic Unit: Cardiology
Language: English
Resource Type: Journal article