Applying induced fit in drug discovery: Square pegs and round holes?

F. Spyrakis; P. Cozzini; A. Sarkar; G.E. Kellogg

doi:10.2174/156802611794863553

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Journal article

Applying induced fit in drug discovery: Square pegs and round holes?

F. Spyrakis, P. Cozzini, A. Sarkar and G.E. Kellogg

Current Topics in Medicinal Chemistry, Vol.11(2), p.131

2011

DOI: https://doi.org/10.2174/156802611794863553

Abstract

catalysis

crystallization

drug research

drug screening

drug structure

editorial

ionic strength

molecular docking

molecular dynamics

nuclear magnetic resonance

pH measurement

protein binding

protein conformation

temperature sensitivity

X ray crystallography

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Details

Title: Applying induced fit in drug discovery: Square pegs and round holes?
Creators: F. Spyrakis
P. Cozzini
A. Sarkar
G.E. Kellogg - Virginia Commonwealth University
Publication Details: Current Topics in Medicinal Chemistry, Vol.11(2), p.131
Publisher: Bentham Science Publishers
Identifiers: 991006118971902656
Language: English
Resource Type: Journal article