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Biomechanical Effects of Proximal Polyetheretherketone Rod Extension on the Upper Instrumented and Adjacent Levels in a Human Long-Segment Construct: A Cadaveric Model
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Biomechanical Effects of Proximal Polyetheretherketone Rod Extension on the Upper Instrumented and Adjacent Levels in a Human Long-Segment Construct: A Cadaveric Model

Bernardo de Andrada Pereira, Jennifer N. Lehrman, Anna G. U. Sawa, Piyanat Wangsawatwong, Jakub Godzik, David S. Xu, Jay D. Turner, Brian P. Kelly and Juan S. Uribe
Neurospine, Vol.19(3), pp.828-837
09/01/2022
PMID: 36203305

Abstract

Clinical Neurology Life Sciences & Biomedicine Neurosciences & Neurology Science & Technology Surgery
Objective: The high mechanical stress zone at the sudden transition from a rigid to flexible region is involved in proximal junctional kyphosis (PJK) physiopathology. We evaluated the biomechanical performance of polyetheretherketone (PEEK) rods used as a nontraditional long semirigid transition phase from a long-segment metallic rod construct to the nonfused thoracic spine.Methods: Pure moment range of motion (ROM) tests (7.5 Nm) were performed on 7 ca-daveric spine segments followed by compression (200 N). Specimens were tested in the fol-lowing conditions: (1) intact; (2) T10-pelvis pedicle screws and rods (PSRs); and (3) ex-tending the proximal construct to T6 using PEEK rods (PSR+PEEK). T10-11 rod strain, T9 anterolateral bone strain, and T10 screw bending moments were analyzed.Results: At the upper instrumented vertebra (UIV)+1, PSR+PEEK versus PSR significantly decreased ROM in flexion (115%, p = 0.02), extension (104%, p = 0.003), left lateral bend-ing (46%, p = 0.02), and right lateral bending (63%, p = 0.008). Also, at UIV+1, PSR+PEEK versus intact significantly decreased ROM in flexion (111%, p = 0.01) and extension (105%, p = 0.003). The UIV+1 anterior column bone strain was significantly reduced with PSR+ PEEK versus PSR during right lateral bending (p = 0.02). Rod strain polarities reversed with PEEK rods in all loading directions except compression.Conclusion: Extending a long-segment construct using PEEK rods caused a decrease in ad-jacent-level hypermobility as a consequence of long-segment immobilization and also redis-tributed the strain on the UIV and adjacent levels, which might contribute to PJK physio-pathology. Further studies are necessary to observe the clinical outcomes of this technique.
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https://doi.org/10.14245/ns.2244146.073View
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