Author contributions: M. A. M. P. C.-L. and J. M. M were the topic editors for this article and developed the key question using the Population, Intervention, Comparator, Outcome (PICO) format in collaboration with R. S. I. B. I. was the appointed methodologist and was among the investigators who conducted the systematic review that formed the basis for the suggestions. M. A. M. wrote the first draft; P. C.-L. B. I. J. M. M. and R. S. I. reviewed and contributed to subsequent versions. Financial/nonfinancial disclosures: The authors have reported to CHEST the following: J. M. M. received monetary support for consultancy at a 1-day, US Chronic Cough Expert Input Forum sponsored by Merck & Co. Inc. None declared (M. A. M. P. C. L. B. I. R. S. I.). ∗Expert Cough Panel Collaborators: Todd M. Adams, MD (Webhannet Internal Medicine Associates of York Hospital, Wells, ME), Kenneth W. Altman, MD, PhD (Geisinger Commonwealth School of Medicine, Danville, PA), Elie Azoulay, MD, PhD (University of Paris, Paris, France), Alan F. Barker, MD (Oregon Health & Science University, Portland, OR), Surinder S. Birring, MB ChB, MD (Division of Asthma, Allergy and Lung Biology, King's College London, London, England), Fiona Blackhall, MD, PhD (Department of Medical Oncology, University of Manchester, Manchester, England), Donald C. Bolser, PhD (College of Veterinary Medicine, University of Florida, Gainesville, FL), Louis-Philippe Boulet, MD, FCCP (Institut universitaire de cardiologie et de pneumologie de Québec, Quebec, QC, Canada), Sidney S. Braman, MD, FCCP (Mount Sinai Hospital, New York, NY), Christopher Brightling, MBBS, PhD, FCCP (University of Leicester, Glenfield Hospital, Leicester, England), Priscilla Callahan-Lyon, MD (Adamstown, MD), Anne B. Chang, MBBS, PhD, MPH (Royal Children's Hospital, Brisbane, QLD, Australia), Paul Davenport, PhD (Department of Physiological Sciences, University of Florida, Gainesville FL), Ali A. El Solh, MD, MPH (University at Buffalo, State University of New York, Buffalo, NY), Patricio Escalante, MD, MSc, FCCP (Mayo Clinic, Rochester, MN), Stephen K. Field, MD (University of Calgary, Calgary, AB, Canada), Dina Fisher, MD, MSc (Respiratory Medicine, University of Calgary, Calgary, AB, Canada), Cynthia T. French, PhD, FCCP (UMass Memorial Medical Center, Worcester, MA), Peter Gibson, MBBS (Hunter Medical Research Institute, New Lambton Heights, NSW, Australia), Cameron Grant, MBChB, PhD (University of Auckland, Auckland, New Zealand), Susan M. Harding, MD, FCCP (Division of Pulmonary, Allergy and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL), Anthony Harnden, MB ChB, MSc (University of Oxford, Oxford, England), Adam T. Hill, MBChB, MD (Royal Infirmary and University of Edinburgh, Edinburgh, Scotland), Richard S. Irwin, MD, Master FCCP (UMass Memorial Medical Center, Worcester, MA), Peter J. Kahrilas, MD (Feinberg School of Medicine, Northwestern University, Chicago, IL), Joanne Kavanagh, MBChB (Division of Asthma, Allergy and Lung Biology, King's College London, London, England), Karina A. Keogh, MD (Mayo Clinic, Rochester, MN), Kefang Lai, MD, PhD (First Affiliated Hospital of Guangzhou Medical College, Guangzhou, China), Andrew P. Lane, MD (Johns Hopkins University School of Medicine, Baltimore, MD), Craig Lilly, MD, FCCP (UMass Memorial Medical Center, Worcester, MA), Kaiser Lim, MD (Mayo Clinic, Rochester, MN), Mark Lown, MBBS, PhD (University of Southampton, Aldermoor Health Centre, Aldermoor Close, Southampton, England), J. Mark Madison, MD, FCCP (UMass Memorial Medical Center, Worcester, MA), Mark A. Malesker, PharmD, FCCP (Creighton University School of Pharmacy and Health Professions, Omaha, NE), Stuart Mazzone, PhD, FCCP (University of Queensland, Brisbane, QLD, Australia), Lorcan McGarvey, MD (Queen's University Belfast, Belfast, Northern Ireland), Alex Molassoitis, PhD, MSc, RN (Hong Kong Polytechnic University, Hong Kong, China), M. Hassan Murad, MD, MPH (Mayo Clinic, Rochester, MN), Mangala Narasimhan, DO, FCCP (Hofstra-Northwell Health, Manhasset, NY), John Oppenheimer, MD (University of Medicine and Dentistry of New Jersey-Rutgers University, Newark, NJ), Mark Rosen, MD, Master FCCP (Icahn School of Medicine at Mount Sinai, New York, NY), Bruce Rubin, MEngr, MD, MBA (Virginia Commonwealth University, Richmond, VA), Richard J. Russell, MBBS (University of Leicester, Glenfield Hospital, Leicester, England), Jay H. Ryu, MD, FCCP (Mayo Clinic, Rochester, MN), Sonal Singh, MD, MPH (UMass Memorial Medical Center, Worcester, MA), Maeve P. Smith, MB ChB, MD (University of Alberta, Edmonton, AB, Canada), Susan M. Tarlo, MBBS, FCCP (Toronto Western Hospital, Toronto, ON, Canada), Anne E. Vertigan, PhD, MBA, BAppSc (SpPath) (John Hunter Hospital, New Lambton Heights, NSW, Australia), Other contributions: We thank Nancy Harger, MLS, clinical service librarians working in the University of Massachusetts Medical School Library, Worcester, MA, who undertook all the searches for this systematic review. Role of sponsors: The American College of Chest Physicians was the sole supporter of these guidelines, this article, and the innovations addressed within. Additional information: The e-Appendix can be found in the Supplemental Materials section of the online article. CHEST Expert Panel Collaborator, Mark Rosen, MD, FCCP, died July 2, 2019. FUNDING/SUPPORT: CHEST was the sole supporter of these guidelines, this article, and the innovation addressed within.