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Complete and prolonged response to immune checkpoint blockade in pole-mutated colorectal cancer
Journal article   Open access

Complete and prolonged response to immune checkpoint blockade in pole-mutated colorectal cancer

R. Silberman, D. F. Steiner, A. A. Lo, A. Gomez, J. L. Zehnder, G. Chu and C. J. Suarez
JCO Precision Oncology, Vol.3
2019
DOI: https://doi.org/10.1200/PO.18.00214

Abstract

bevacizumab capecitabine carcinoembryonic antigen fluorouracil hemoglobin irinotecan nivolumab oxaliplatin pembrolizumab regorafenib tipiracil trifluridine adult allergic reaction Article cancer growth cancer palliative therapy cancer patient cancer staging case report clinical article colostomy cystectomy drug withdrawal fatigue gene herpes zoster histology Horner syndrome human ileal conduit immune response intraoperative radiotherapy lymph node lymph node metastasis male metastatic colorectal cancer microsatellite instability mismatch repair next generation sequencing oncogene K ras pancytopenia pole gene polymerase chain reaction positron emission tomography postoperative complication priority journal ptosis (eyelid) rectum anterior resection sigmoid small intestine resection somatic mutation staining supraclavicular lymph node thorax radiography treatment response tumor associated leukocyte tumor cell tumor volume x-ray computed tomography
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https://doi.org/10.1200/PO.18.00214View
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