Doxycycline Induced Pancreatitis: An Uncommon Complication of a Common Drug

William Reiche; Faith Abodunrin; Chris Destache; Rajani Rangray; Manasa Velagapudi

doi:10.3390/pharmacy10060144

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Doxycycline Induced Pancreatitis: An Uncommon Complication of a Common Drug

Journal article

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Doxycycline Induced Pancreatitis: An Uncommon Complication of a Common Drug

William Reiche, Faith Abodunrin, Chris Destache, Rajani Rangray and Manasa Velagapudi

Pharmacy, Vol.10(6), p.144

10/30/2022

DOI: https://doi.org/10.3390/pharmacy10060144

PMID: 36412820

Abstract

adverse drug reaction

Case Report

DIAP

DIP

doxycycline

drug induced acute pancreatitis

We describe the risk factors for the development, timing, and severity of doxycycline induced acute pancreatitis (DIAP) in two case reports and a review of prior published cases, to better understand DIAP. Clinicians must maintain a high level of suspicion for DIAP in patients presenting with acute pancreatitis, while on doxycycline therapy. The latency and severity of DIAP are variable, making diagnosis challenging. Treatment includes bowel rest, hydration, and discontinuation of doxycycline.

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Title: Doxycycline Induced Pancreatitis: An Uncommon Complication of a Common Drug
Creators: William Reiche - CHI Health Creighton University Medical Center - Bergan Mercy
Faith Abodunrin - Department of Medicine, CHI Health Creighton University Medical Center, Omaha, NE 68124, USA Department of Pharmacy Practice, Creighton University School of Pharmacy and Health Professions, Omaha, NE 68178, USA Division of Gastroenterology and Hepatology, CHI Creighton University Medical Center, Omaha, NE 68124, USA Division of Infectious Diseases, CHI Creighton University Medical Center, Omaha, NE 68124, USA
Chris Destache - Department of Medicine, CHI Health Creighton University Medical Center, Omaha, NE 68124, USA Department of Pharmacy Practice, Creighton University School of Pharmacy and Health Professions, Omaha, NE 68178, USA Division of Gastroenterology and Hepatology, CHI Creighton University Medical Center, Omaha, NE 68124, USA Division of Infectious Diseases, CHI Creighton University Medical Center, Omaha, NE 68124, USA
Rajani Rangray - Creighton University
Manasa Velagapudi - Department of Medicine, CHI Health Creighton University Medical Center, Omaha, NE 68124, USA Department of Pharmacy Practice, Creighton University School of Pharmacy and Health Professions, Omaha, NE 68178, USA Division of Gastroenterology and Hepatology, CHI Creighton University Medical Center, Omaha, NE 68124, USA Division of Infectious Diseases, CHI Creighton University Medical Center, Omaha, NE 68124, USA
Publication Details: Pharmacy, Vol.10(6), p.144
Publisher: MDPI
Identifiers: 991005966048702656
Academic Unit: Infectious Disease; Gastroenterology
Language: English
Resource Type: Journal article