Abstract
Palliative care (PC) has been shown to improve quality of life (QoL), reduce symptom burden, and align care with patient goals in those with serious illnesses. However, its integration into the emergency department (ED), where many patients with advanced illness present, remains underexplored and inconsistently applied. This narrative review evaluates several recent studies on ED-based palliative care, aiming to clarify whether the early benefits in symptom management and QoL are associated with reduced healthcare utilization and cost. A comprehensive literature search identified five new key studies with significant methodological differences, including variations in patient populations, outcome measures, and study designs. Some studies demonstrated short-term symptom relief, yet only one showed significant improvements in QoL at long-term follow-up. For healthcare utilization, still only one of these new studies reported substantial cost savings, underscoring the need for further research to validate financial benefits. We suggest how future work should be designed to explore both clinical and economic outcomes in tandem to establish a clear value proposition for ED-based palliative care. By addressing this lack of cohesion, we can determine the merit of ED-palliative care integrations with the goal of improving patient care and optimizing resource utilization. © 2025 Elsevier B.V., All rights reserved.