Funding for this research was provided by Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Kenilworth, NJ, USA. Medical writing assistance, under direction of the authors, was provided by Annette Smith, PhD, of CMC AFFINITY, Complete Medical Communications, in accordance with Good Publication Practice (GPP3) guidelines. This assistance was funded by Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Kenilworth, NJ, USA. We also thank Boyd B. Scott (Merck & Co., Inc., Kenilworth, NJ, USA) for editorial support, Steven Doleckyj who was the project manager for this study, Paul Miller who provided study materials or patients, and all of the clinical scientists and the patients who donated biopsies. Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Kenilworth, NJ, USA's data sharing policy, including restrictions, is available at http://engagezone.msd.com/ds_documentation.php. Requests for access to the clinical study data can be submitted through the EngageZone site or via email to dataaccess@merck.com. Authors' roles: All authors take responsibility for the integrity of the data analysis. Author's Contribution: Conception, design or planning the study: DC, RR, AS; Acquisition of data: RR, BL, CAFZ, IV; Analysis of data: DC, HG, RR, AS, SC, LTD; Interpretation of results: DC, DD, HG, RR, AS, BL, TdV, GE, CAFZ, IV, LTD; All authors contributed to the drafting, reviewing or revising of the manuscript.
Funding Information:
Funding for this research was provided by Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Kenilworth, NJ, USA. Medical writing assistance, under direction of the authors, was provided by Annette Smith, PhD, of CMC AFFINITY, Complete Medical Communications, in accordance with Good Publication Practice (GPP3) guidelines. This assistance was funded by Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Kenilworth, NJ, USA. We also thank Boyd B. Scott (Merck & Co., Inc., Kenilworth, NJ, USA) for editorial support, Steven Doleckyj who was the project manager for this study, Paul Miller who provided study materials or patients, and all of the clinical scientists and the patients who donated biopsies. Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Kenilworth, NJ, USA's data sharing policy, including restrictions, is available at http://engagezone.msd.com/ds_documentation.php . Requests for access to the clinical study data can be submitted through the EngageZone site or via email to dataaccess@merck.com .
Funding Information:
RR received funds from Merck & Co., Inc., Kenilworth, NJ, USA to process the biopsies for the trial. DD has received grants from Amgen and Eli Lilly & Co.; consulting fees from Amgen, Eli Lilly & Co., Merck & Co., Inc., Kenilworth, NJ, USA, Radius Health, and Tarsa; speaking fees from Amgen and Eli Lilly & Co.; and medical writing fees from Radius Health. BL has, on behalf of her institution, received a grant from Merck & Co., Inc., Kenilworth, NJ, USA for conducting the trial; has received grants from Eli Lilly & Co., Novo Nordisk, and Orkla Health for research support; and has received personal fees from Amgen, Eli Lilly & Co., Merck & Co., Inc., Kenilworth, NJ, USA, and UCB for advisory boards and lectures. HG, SC, DC, AS, and LTD are, or were at the time of study conduct, employees of Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Kenilworth, NJ, USA, and may own stock and/or stock options in the company. TdV has received consulting fees from Merck & Co., Inc., Kenilworth, NJ, USA; speaking fees from Abbott, Aspen, Adcock Ingram, Bayer, Merck & Co., Inc., Kenilworth, NJ, USA, and Pfizer; and personal fees from Amgen, Adcock Ingram, and Pfizer for advisory boards. CAFZ has received a grant for research from Merck & Co., Inc., Kenilworth, NJ, USA. GE and IV have no conflicts of interest.