Abstract
In the present investigation, the effects of the MAO inhibitors, iproniazid, pargyline and tranylcypromine, as well as d-amphetamine or phencyclidine induced stereotyped behavior in rats has been evaluated. We have previously reported that phencyclidine produces a very characteristic stereotyped behavioral syndrome in rats. The possibility of a pharmacokinetic interaction between these compounds was evaluated by measuring the brain levels of phencyclidine and its metabolites in the various pretreatment groups.