Asymmetric synthetic methodology is introduced for preparation of 3,3-disubstituted cyclopentanones, including (+)-α-cuparenone, of high enantiomeric purity.
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Title
Enantiocontrolled synthesis of quaternary carbon centers. 3,3-Disubstituted cyclopentanones. (+)-α-cuparenone.
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Gary H. Posner (Author) - Johns Hopkins University
Timothy P. Kogan (Author) - Johns Hopkins University
Martin Hulce (Author) - Johns Hopkins University
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Clark, Terry D.; Potter, Joshua D.; Larson, Jennifer M.; Mordeson, John N.; Wierman, Mark J.