FXa-mediated PAR-2 promotes the efficacy of immunotherapy for hepatocellular carcinoma through immune escape and anoikis resistance by inducing PD-L1 transcription

Journal article

Open access

Peer reviewed

Xuemei Li, Lei Gao, Bofang Wang, Jike Hu, Yang Yu, Baohong Gu, Lin Xiang, Xiaomei Li, Haiyuan Li, Tao Zhang, …

Journal for immunotherapy of cancer, Vol.12(7), p.e009565

07/25/2024

PMID: 39060025

Abstract

Clinical/Translational Cancer Immunotherapy

Original Research

url

https://doi.org/10.1136/jitc-2024-009565View

Published (Version of record) Open

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Title: FXa-mediated PAR-2 promotes the efficacy of immunotherapy for hepatocellular carcinoma through immune escape and anoikis resistance by inducing PD-L1 transcription
Creators: Xuemei Li - Lanzhou University Second Hospital
Lei Gao - Lanzhou University Second Hospital
Bofang Wang - Lanzhou University Second Hospital
Jike Hu - Lanzhou University
Yang Yu - Lanzhou University
Baohong Gu - Lanzhou University
Lin Xiang - Lanzhou University
Xiaomei Li - Lanzhou University Second Hospital
Haiyuan Li - Lanzhou University
Tao Zhang - First Hospital of Lanzhou University
Yunpeng Wang - Lanzhou University
Chenhui Ma - Lanzhou University Second Hospital
Jiahong Dong - Tsinghua University
Jianrong Lu - Florida College
Alexandra Lucas - Arizona State University
Hao Chen - Lanzhou University Second Hospital
Publication Details: Journal for immunotherapy of cancer, Vol.12(7), p.e009565
Publisher: BMJ Publishing Group
Grant note: GXH20230817-14 / ; CY2023-ZD01 / ; 2020JSCX0073; 2020SHFZ0039 / ; 2019RCXM020 / ; 22ZD6FA054 / ; 82160129 / ; lzuyxcx-2022-160; lzuyxcx-2022-45; lzuyxcx-2022-88 / ;
Identifiers: 991006105481202656
Academic Unit: Hospital Medicine
Language: English
Resource Type: Journal article