Generation of leukotriene B4 and C4 from granulocytes of normal controls, allergic rhinitis, and asthmatic subjects

F. Kohi; H. Miyagawa; D. K. Agrawal; A. K. Bewtra; R. G. Townley

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Generation of leukotriene B4 and C4 from granulocytes of normal controls, allergic rhinitis, and asthmatic subjects

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Generation of leukotriene B4 and C4 from granulocytes of normal controls, allergic rhinitis, and asthmatic subjects

F. Kohi, H. Miyagawa, D. K. Agrawal, A. K. Bewtra and R. G. Townley

Annals of allergy, Vol.65(3), pp.228-232

01/01/1990

PMID: 2169715

Abstract

Immunology and Allergy

We determined the relationship of allergic disease to the number and activity of eosinophils and their production of leukotriene B4 and leukotriene C4 (leukotriene D4 equivalents). Granulocytes from allergic rhinitis (AR) subjects and asthmatics release more LTC4 than normals. Furthermore, eosinophils of astmatics generate more LTC4 than those of AR subjects.

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Title: Generation of leukotriene B4 and C4 from granulocytes of normal controls, allergic rhinitis, and asthmatic subjects
Creators: F. Kohi (Author) - Creighton University
H. Miyagawa (Author) - Creighton University
D. K. Agrawal (Author) - Creighton University
A. K. Bewtra (Author) - Creighton University
R. G. Townley (Author) - Department of Medicine
Additional links: Clark, Terry D.; Potter, Joshua D.; Larson, Jennifer M.; Mordeson, John N.; Wierman, Mark J.
Publication Details: Annals of allergy, Vol.65(3), pp.228-232
Series: 65
Number of pages: 5
Identifiers: 991005929005502656
Academic Unit: General Medicine
Language: English
Resource Type: Journal article

Generation of leukotriene B4 and C4 from granulocytes of normal controls, allergic rhinitis, and asthmatic subjects

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