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Hemorrhage of cavernous malformations during pregnancy and in the peripartum period: causal or coincidence? Case report and review of the literature
Journal article   Open access   Peer reviewed

Hemorrhage of cavernous malformations during pregnancy and in the peripartum period: causal or coincidence? Case report and review of the literature

Sam Safavi-Abbasi, Iman Feiz-Erfan, Robert F Spetzler, Louis Kim, Seref Dogan, Randall W Porter and Volker K H Sonntag
Neurosurgical focus, Vol.21(1), pp.e12-4
07/15/2006
PMID: 16859250

Abstract

Adult Cesarean Section Disease Progression Early Diagnosis Emergency Treatment - standards Female Hemangioma, Cavernous, Central Nervous System - complications Hemangioma, Cavernous, Central Nervous System - physiopathology Hemangioma, Cavernous, Central Nervous System - surgery Hemorrhage - etiology Hemorrhage - prevention & control Hemorrhage - surgery Humans Magnetic Resonance Imaging Neurosurgical Procedures - methods Paresthesia - etiology Paresthesia - physiopathology Pregnancy Pregnancy Complications, Neoplastic - diagnosis Pregnancy Complications, Neoplastic - etiology Pregnancy Complications, Neoplastic - physiopathology Spinal Cord - blood supply Spinal Cord - pathology Spinal Cord - physiopathology Spinal Cord Neoplasms - complications Spinal Cord Neoplasms - physiopathology Spinal Cord Neoplasms - surgery Thoracic Vertebrae Treatment Outcome Vascular Surgical Procedures - methods Veins - abnormalities Veins - pathology Veins - physiopathology
There is growing evidence to suggest that pregnancy may increase the risk of hemorrhage from cavernous malformations (CMs). In the present case, a 21-year-old primigravida was admitted to the authors' neurosurgical service after a cesarean section. Three weeks before admission she had experienced rapidly progressive bilateral lower-extremity paresthesias. Spinal magnetic resonance (MR) imaging revealed the presence of an intramedullary thoracic lesion. On T2-weighted MR images, heterogeneous signal intensity with a rim of decreased intensity was demonstrated in the spine. The mass was successfully resected, and 1 year later the patient's symptoms had resolved completely. This is the fourth reported case of a spinal intramedullary CM that became symptomatic during pregnancy. The pathogenesis and management of this entity are reviewed.
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https://doi.org/10.3171/foc.2006.21.1.13View
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