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Identification of myofilament mutations: Its role in the diagnosis and management of hypertrophic cardiomyopathy
Journal article

Identification of myofilament mutations: Its role in the diagnosis and management of hypertrophic cardiomyopathy

S. Dandona and R. Roberts
Mayo Clinic proceedings, Vol.83(6)
2008
DOI: https://doi.org/10.4065/83.6.626

Abstract

3 hydroxy 3 methylglutaryl coenzyme A angiotensin 2 receptor antagonist atorvastatin beta tropomyosin collagen farnesyl diphosphate geranylgeranyl pyrophosphate hydroxymethylglutaryl coenzyme A reductase inhibitor losartan myosin binding protein C myosin heavy chain beta simvastatin tropomyosin troponin T attributable risk cardiovascular risk defibrillation defibrillator diastolic dysfunction editorial exercise gene mutation genetic association genetic disorder genotype heart death heart left ventricle contraction heart muscle fibrosis hypertrophic cardiomyopathy mutational analysis myofilament phenotype protein processing rabbit stroke systolic dysfunction transgenic animal

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