Abstract
Primary squamous cell carcinoma (SCC) invasive into the lamina propria (stage T1) and squamous cell carcinoma in situ (SCCIS) (Stage Tis) are considered high risk and are associated with poor prognoses, even when the disease is non-muscle invasive. Therefore, radical cystectomy is usually considered the first-line standard of care. However, in patients who are poor surgical candidates, intravesical mitomycin may be a reasonable treatment option.
In this case report, the patient was initially treated for non-muscle-invasive urothelial carcinoma with local resection and intravesical bacillus Calmette-Guerin (BCG) and after 20 years of recurrence-free surveillance, he developed non-muscle-invasive stage T1, Tis bladder SCC. This case report supports long-term surveillance of bladder cancer. (C) 2014 Elsevier Inc. All rights reserved.