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Laboratory and Clinical Efficacy of 6% Hydrogen Peroxide At-Home Whitening Systems with Custom Trays
Journal article   Open access   Peer reviewed

Laboratory and Clinical Efficacy of 6% Hydrogen Peroxide At-Home Whitening Systems with Custom Trays

Mayumi Maesako, Nagisa Matsui, Miyuki Oshika, Masao Irie and Akimasa Tsujimoto
Bioengineering (Basel), Vol.13(7), p.815
07/16/2026

Abstract

Demand for fast and convenient dental whitening has increased in recent years. This paper compares the efficacy of three home whitening systems (TiON Take Home with (W), Opalescence Go (G), and Angelus Home 16% (A)) and presents a clinical case. W and G contain 6% hydrogen peroxide, while A contains 16% carbamide peroxide, approximately equal active peroxide contents. The whitening agents were applied to brown chicken eggshells for 90 (W90, G90, A90) or 60 (W60) minute periods ten (W90, W60, G90) or fourteen (A90) times. The color was measured before treatment, and after 3, 5, 7, 10, 12, and 14 applications. ∆E*ab was calculated at each point. ∆E*ab at completion were 4.97 (A90), 7.25 (G90), 9.84 (W60), and 14.96 (W90). A clinical study of the efficacy of W60 found a ∆E*ab of 4.18. The whitening efficacy of a system is not determined entirely by the content of active peroxide.
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https://doi.org/10.3390/bioengineering13070815View
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