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Lemons in the Arizona Sunshine: The Effects of Furocoumarins Leading to Phytophotodermatitis and Burn-like Injuries
Journal article   Peer reviewed

Lemons in the Arizona Sunshine: The Effects of Furocoumarins Leading to Phytophotodermatitis and Burn-like Injuries

Marc R Matthews, Joel C VanderVelde, Daniel M Caruso and Kevin N Foster
Wounds (King of Prussia, Pa.), Vol.29(12), pp.E118-E124
12/2017
PMID: 29324427

Abstract

Administration, Topical Arizona Burns - etiology Burns - pathology Burns - therapy Child Child Abuse Citrus - adverse effects Citrus - chemistry Debridement Dermatitis, Phototoxic - etiology Dermatitis, Phototoxic - pathology Dermatitis, Phototoxic - therapy Diagnosis, Differential Female Furocoumarins - adverse effects Furocoumarins - chemistry Humans Sunlight - adverse effects Treatment Outcome Ultraviolet Rays - adverse effects
Phytophototoxic dermatitis is a strong phototoxic reaction to ultraviolet A (UV-A) radiation exposure after cutaneous contact with citrus fruit containing furocoumarins, leading to skin injury. At the Arizona Burn Center (Phoenix, AZ), the majority of these injuries are managed in the outpatient setting. The authors present a pediatric admission for burn-like injuries following prolonged cutaneous exposure to lemons while playing in the Arizona sunshine. A 7-year-old girl playing in her backyard squeezed lemon juice onto her skin while in the hot Arizona sunshine; within 24 hours, the child experienced pain, erythema, and blistering to multiple areas of her skin. She was admitted to the authors' burn center for wound care and pain control. She had scattered first-degree and second-degree burn-like lesions to her face, neck, and chest as well as bilateral forearms, hands, lower extremities, and feet. After blister debridement, appropriate dressing care, and pain medication, the patient was discharged home after 4 days of hospitalization with appropriate clinical follow-up. Burn-like lesions caused by furocoumarins after cutaneous absorption and UV-A exposure are known clinical entities in Arizona. The sequential progression from erythema to blisters equivalent to second-degree burn-like lesions to cutaneous hyperpigmentation is a well-described clinical triad. Meticulous wound care and pain control for the treatment of these burn-like lesions are essential as is the need for the wound care specialist to be well versed on this topic to quickly identify the etiology of the injury, thereby avoiding misdiagnosing the patient with nonaccidental traumatic injuries.

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