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Oncologic outcomes after robot-assisted versus laparoscopic distal pancreatectomy: Analysis of the National Cancer Database
Journal article   Peer reviewed

Oncologic outcomes after robot-assisted versus laparoscopic distal pancreatectomy: Analysis of the National Cancer Database

Mustafa Raoof, Carolijn L. M. A. Nota, Laleh G. Melstrom, Susanne G. Warner, Yanghee Woo, Gagandeep Singh and Yuman Fong
Journal of Surgical Oncology, Vol.118(4)
2018

Abstract

Adenocarcinoma Databases, Factual Female Follow-Up Studies Humans Laparoscopy Male Margins of Excision Middle Aged Pancreatectomy Pancreatic Neoplasms Robotic Surgical Procedures Survival Rate Treatment Outcome antineoplastic agent adult Article cancer chemotherapy cancer mortality cancer surgery cancer survival chemoradiotherapy demography distal pancreatectomy female hospital readmission human laparoscopic surgery length of stay lymph node metastasis major clinical study male middle aged outcome assessment overall survival pancreas adenocarcinoma priority journal robot assisted surgery adenocarcinoma factual database follow up laparoscopy mortality pancreas tumor pancreatectomy pathology robotic surgical procedure surgical margin survival rate treatment outcome
Background: How the oncologic outcomes after robotic distal pancreatectomy (RDP) compare to those after laparoscopic distal pancreatectomy (LDP) remains unknown. Methods: Using the National Cancer Database (NCDB), we analyzed all patients undergoing LDP or RDP for resectable pancreatic adenocarcinoma over a 4-year period (2010-2013). Results: Of the 704 eligible patients, 605 (86%) underwent LDP and 99 (14%) underwent RDP. The median follow-up for patients was 25 months. There were no differences in the two groups with respect to sociodemographic, clinicopathologic, or treatment characteristics. On comparing LDP versus RDP, there was no difference in the margin-positive rate (15% vs 16%; P = 0.84); lymph nodes examined (12 vs 11; P = 0.67); overall survival (hazard ratio [HR], 1.1, 95% confidence intervals [CI], 0.7 to 1.7; 28 vs 25 months; P = 0.71); hospital stay (6 vs 5 days; P = 0.14); time to chemotherapy (50 vs 52 days; P = 0.65); 30-day readmission (9.4% vs 9.1%; P = 0.92); and mortality (1% vs 0%; P = 0.28). Patients undergoing LDP had a significantly higher conversion rate to open or minimally invasive pancreatic cancer resections compared with RDP (27% vs 10%; P < 0.001). Conclusion: The early national experience with RDP demonstrates similar oncologic outcomes to LDP, with a significantly lower conversion rate. © 2018 Wiley Periodicals, Inc.

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