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Parasitic Persistence: The Diagnostic Challenge of Strongyloidiasis in a Non-Endemic Setting
Journal article   Open access   Peer reviewed

Parasitic Persistence: The Diagnostic Challenge of Strongyloidiasis in a Non-Endemic Setting

Alexander Siegel, Jennifer Gamache, Kyaw Min Tun and Wuttiporn Manatsathit
Gastro hep advances, p.101014
05/2026

Abstract

duodenal erosions eosinophilia gastrointestinal bleeding infectious colitis Strongyloidiasis
Strongyloidiasis, is a parasitic infection endemic to warm, and moist climates, that is caused by the intestinal nematode Strongyloides stercoralis. In the United States, most cases are seen in immunocompromised patient’s residing in the Northeast and East South-Central regions and travelers from endemic regions. While often underrecognized, Strongyloides infection should remain a key consideration in patients presenting with atypical gastrointestinal (GI) symptoms, with a relevant exposure history. We present a case of a 45-year-old male initially diagnosed with Heliobacter pylori whose symptoms persisted and was ultimately diagnosed with Strongyloides infection.
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https://doi.org/10.1016/j.gastha.2026.101014View
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