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Photodistributed RIME Syndrome Treated With Etanercept
Journal article   Peer reviewed

Photodistributed RIME Syndrome Treated With Etanercept

Elika D Javaheri, Dana Harb, Amanda Damon, Bo Borch-Christensen and Elizabeth Dupuy
Pediatric dermatology
06/14/2026
PMID: 42289385

Abstract

RIME Stevens‐Johnson syndrome reactive infectious mucocutaneous eruption etanercept photodistributed
Reactive infectious mucocutaneous eruption (RIME) is a post-infectious mucositis which primarily affects pediatric patients. We report a 14-year-old girl with recent intensive sun exposure who developed RIME in a photodistributed pattern. Treatment with etanercept yielded clinical improvement. Potential mechanisms underlying photodistributed RIME syndrome are discussed, with comparison to photodistributed instances of Stevens-Johnson syndrome.

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