Abstract
We believe current evidence does not support the widespread or routine application of extracorporeal treatment to adults with severe hypoxemic respiratory failure, including that due to A(H1N1) influenza infection. We believe the best clinical trial data are those provided by the first two clinical trials in spite of the differences in treatment between current and past eras.8,9 We conclude that the benefits of ECMO treatment in A(H1N1)-related hypoxemic lung failure are unproven and therefore cannot be considered rescue therapy. © 2010 American College of Chest Physicians.