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Reciprocal Changes in Sagittal Spinal Alignment After L5-S1 Anterior Lumbar Interbody Fusion
Journal article   Peer reviewed

Reciprocal Changes in Sagittal Spinal Alignment After L5-S1 Anterior Lumbar Interbody Fusion

James J. Zhou, Nima Alan, Charuta G. Furey, Luke K. O'Neill, Juan P. Giraldo, Zaman Mirzadeh, Jay D. Turner and Juan S. Uribe
World neurosurgery, Vol.188, pp.e64-e70
08/01/2024
PMID: 38754550

Abstract

Clinical Neurology Life Sciences & Biomedicine Neurosciences & Neurology Science & Technology Surgery
OBJECTIVE: Degenerative diseases of the lumbar spine decrease lumbar lordosis (LL). Anterior lumbar interbody fusion (ALIF) at the L5-S1 disc space improves segmental lordosis, LL, and sagittal balance. This study investigated reciprocal changes in spinopelvic alignment after L5-S1 ALIF.- METHODS: A retrospective chart review identified patients who underwent L5-S1 ALIF with or without posterior fixation at a single institution (November 1, 2016 to October 1, 2021). Changes in pelvic tilt, sacral slope, proximal LL (L1-L4), distal LL (L4-S1), total LL (L1-S1), segmental lordosis, pelvic incidence- LL mismatch, thoracic kyphosis, cervical lordosis, and sagittal vertical axis were measured on preoperative and postoperative radiographs. RESULTS: Forty-eight patients were identified. Immediate postoperative radiographs were obtained at a mean (SD) of 17 (20) days after surgery; delayed radiographs were obtained 184 (82) days after surgery. After surgery, patients had significantly decreased pelvic tilt (15.71 degrees [7.25 degrees ] vs. 17.52 degrees [7.67 degrees ], P = 0.003) and proximal LL (11.86 degrees [10.67 degrees ] vs. 16.03 degrees [10.45 degrees ], P < 0.001) and increased sacral slope (39.49 degrees [9.27 degrees ] vs. 36.31 degrees [10.39 degrees ], P < 0.001), LL (55.35 degrees [13.15 degrees ] vs. 51.63 degrees [13.38 degrees ], P = 0.001), and distal LL (43.17 degrees [9.33 degrees ] vs. 35.80 degrees [8.02 degrees ], P < 0.001). Segmental lordosis increased significantly at L5-S1 and decreased significantly at L2-3, L3-4, and L4-5. Lordosis distribution index increased from 72.55 (19.53) to 81.38 (22.83) ( P < 0.001). CONCLUSIONS: L5-S1 ALIF was associated with increased L5-S1 segmental lordosis accompanied by pelvic anteversion and a reciprocal decrease in proximal LL. These changes may represent a reversal of compensatory mechanisms, suggesting an overall relaxation of spinopelvic alignment after L5-S1 ALIF.

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