The authors thank the participants and the field center staff for their invaluable contributions to the STURDY trial. The authors thank National Institutes of Health and its Institutes for supporting multiple aspects of this work. STURDY is supported by the National Institute on Aging (U01AG047837). The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by the National Institute on Aging (5U01AG047837-04). Research reported in this publication was supported by the National Institute on Aging of the National Institutes of Health (NIH/NIA) under Award Number U01AG047837. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. The Office of Dietary Supplements (ODS) also supported this research. T.B.P. was sponsored by grants from Health Resources and Services Administration (T32HP10025B0) and National Heart, Lung, and Blood Institute (NHLBI, 2T32HL007180-41A1). S.P.J. was supported by National Institute of Diabetes and Digestive and Kidney Diseases (T32DK007732) and the NHLBI (K23HL135273). K.T.G. and H.N.M. were supported by a predoctoral fellowship in Interdisciplinary Training in Cardiovascular Health Research (T32NR012704). K.T.G. was also supported by a Predoctoral Clinical Research Training Program (TL1TR001078). M.L. was supported by grants from the National Institute of Diabetes and Digestive and Kidney Diseases (R01DK089174, R01DK108784, and U01DK061730), National Heart, Lung, and Blood Institute (UH3HL130688-02), and National Institute of Alcohol Abuse and Alcoholism (U10AA025286).
Funding Information:
Patient portal messages inviting seniors to participate in a randomized controlled trial resulted in a response rate similar to commercial email marketing and resulted in very few complaints or opt-out requests. Furthermore, a longer message with more content enhanced response rate. Recruitment through patient portals might be an effective strategy to enroll trial participants. Clinical trial randomized controlled trial recruitment methods electronic medical records patient portal messages National Institute on Aging https://doi.org/10.13039/100000049 5U01AG047837-04 National Center for Advancing Translational Sciences https://doi.org/10.13039/100006108 UL1TR001079 edited-state corrected-proof The authors thank the participants and the field center staff for their invaluable contributions to the STURDY trial. The authors thank National Institutes of Health and its Institutes for supporting multiple aspects of this work. STURDY is supported by the National Institute on Aging (U01AG047837). Members of the STURDY Collaborative Research Group by center: At Johns Hopkins University Centers: Welch Center for Prevention, Epidemiology and Clinical Research: Lawrence J. Appel, MD, MPH (chair); Nicole Cronin; Stephen P. Juraschek, MD, PhD; Scott McClure, MS; Jennifer Miskimon; Christine M. Mitchell, ScM; Timothy B. Plante, MD, MHS. Center on Aging and Health: Rita R. Kalyani, MD, MHS; David L. Roth, PhD; Jennifer A. Schrack, PhD; Sarah L. Szanton, PhD; Jacek Urbanek, PhD; Jeremy Walston, MD; Amal Wanigatunga, PhD. STURDY Data Coordinating Center: Sheriza N. Baksh, PhD; Amanda L. Blackford, ScM; Shumon Chattopadhyay, MSE; Lea T. Drye, PhD; John Dodge; Cathleen Ewing; Sana Haider, BS; Stephanie C. Holland, BS; Rosetta Jackson; Andrea Lears, BS; Curtis Meinert, PhD; David Shade, JD; Michael Smith, BS; Alice L. Sternberg, ScM; James Tonascia, PhD; Mark L. Van Natta, MHS; Annette Wagoner. Clinical Field Centers, Johns Hopkins University: George W. Comstock Center for Public Health Research and Prevention: Erin D. Michos, MD, MHS (Site PI); J. Denise Bennett; Pamela Bowers; Josef Coresh, MD, PhD; Patricia Crowley, MS; Tammy Crunkleton; Briana Dick, BA; Rebecca Evans, RN; Mary Godwin; Lynne Hammann; Deborah Hawks; Karen Horning; Erika Hull; Brandi Mills; Melissa Minotti, MPH; Leann Raley; Amanda Reed, MS; Rhonda Reeder, RN; Cassie Reid; Melissa Shuda; Adria Spikes; Rhonda Stouffer; Kelly Weicht. ProHealth Clinical Research Unit: Edgar R. Miller III, MD, PhD (Site PI); Caroline Abbas; Bernellyn Carey, BS; Jeanne Charleston, BSN, RN; Syree Davis, BS; Naomi DeRoche-Brown; Debra Gayles, BS; Sherlina Holland; Ina Glenn-Smith; Duane Johnson; Mia Johnson; Eva Keyes; Kristen McArthur; Danielle Santiago; Chanchai Sapun; Valerie Sneed; Lee Swartz, MBA; Letitia Thomas. At the University of Maryland School of Medicine Laboratory: Robert H. Christenson, PhD; Show-Hong Duh, PhD; Heather Rebuck. At the Data and Safety Monitoring Board (DSMB): Clifford Rosen, MD (chair, Maine Medical Center Research Institute); Tom Cook, PhD (University of Wisconsin); Pamela Duncan, PhD (Wake Forest Baptist Health); Karen Hansen, MD, MS (2016-2019, University of Wisconsin); Anne Kenny, MD (2014-2016, University of Connecticut); Sue Shapses, PhD, RD (Rutgers University). At the National Institute on Aging (NIA): Judy Hannah, PhD; Sergei Romashkan, MD. At the Office of Dietary Supplements (ODS): Cindy D. Davis, PhD; Christopher T. Sempos, PhD. Consultants: Jack M. Guralnik, MD, PhD (University of Maryland School of Medicine); J.C. Gallagher, MD (Creighton University School of Medicine). Declaration of conflicting interests The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. Funding The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by the National Institute on Aging (5U01AG047837-04). Research reported in this publication was supported by the National Institute on Aging of the National Institutes of Health (NIH/NIA) under Award Number U01AG047837. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. The Office of Dietary Supplements (ODS) also supported this research. T.B.P. was sponsored by grants from Health Resources and Services Administration (T32HP10025B0) and National Heart, Lung, and Blood Institute (NHLBI, 2T32HL007180-41A1). S.P.J. was supported by National Institute of Diabetes and Digestive and Kidney Diseases (T32DK007732) and the NHLBI (K23HL135273). K.T.G. and H.N.M. were supported by a predoctoral fellowship in Interdisciplinary Training in Cardiovascular Health Research (T32NR012704). K.T.G. was also supported by a Predoctoral Clinical Research Training Program (TL1TR001078). M.L. was supported by grants from the National Institute of Diabetes and Digestive and Kidney Diseases (R01DK089174, R01DK108784, and U01DK061730), National Heart, Lung, and Blood Institute (UH3HL130688-02), and National Institute of Alcohol Abuse and Alcoholism (U10AA025286). Trial registration ClinicalTrials.gov: NCT02166333. ORCID iD Timothy B Plante https://orcid.org/0000-0001-9992-9597 Supplemental material Supplemental material for this article is available online.