Abstract
(2), the number of sites with irreversible segments was adjusted for baseline, and for repeated within-patient, between-site measures. [...]to suggest that a "doubling" of fixed defects in the medical therapy group implies enhanced perfusion in the TMR group is inappropriate, especially because a subgroup analysis of the same TMR patients showed no improvement in myocardial perfusion with PET scanning (3). [...]we believe that the reported benefits of TMR, even out to five years, may be related to the placebo effect.