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Selective cycloalkanone reductions using aluminum amalgam
Journal article   Peer reviewed

Selective cycloalkanone reductions using aluminum amalgam

Martin Hulce and Timothy LaVaute
Tetrahedron Letters, Vol.29(5), pp.525-528
29
1988

Abstract

Biochemistry Drug Discovery Organic Chemistry
Aluminum amalgam in aqueous tetrahydrofuran reduces cycloalkanones to their respective alcohols. The reaction exhibits sensitivity to the ring size and steric environment of the ketone.

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