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The Role of Biologic Therapies in Dermatology
Journal article   Peer reviewed

The Role of Biologic Therapies in Dermatology

Ramin Fathi and April Wang Armstrong
Medical Clinics of North America, Vol.99(6)
2015
DOI: https://doi.org/10.1016/j.mcna.2015.07.008

Abstract

Adalimumab Antibodies, Monoclonal Dermatologic Agents Etanercept Humans Immunoglobulins, Intravenous Infliximab Interleukins Rituximab Skin Diseases Tumor Necrosis Factor-alpha Ustekinumab adalimumab biological product brodalumab etanercept immunoglobulin infliximab ixekizumab placebo recombinant interleukin 1 receptor blocking agent rituximab secukinumab tumor necrosis factor alpha inhibitor ustekinumab adalimumab dermatological agent etanercept immunoglobulin interleukin derivative monoclonal antibody secukinumab tumor necrosis factor alpha ustekinumab acute graft versus host disease adverse drug reaction anaphylaxis anemia aphthous stomatitis B cell lymphoma Behcet disease biological therapy bullous pemphigoid chest tightness chill chronic graft versus host disease chronic lymphatic leukemia clinical decision making dermatology dermatomyositis drug contraindication drug efficacy drug fever drug indication drug induced headache drug labeling drug mechanism drug safety drug targeting drug tolerability epidermolysis bullosa acquisita graft versus host reaction human injection site reaction low back pain meta analysis (topic) microscopic polyangiitis mucocutaneous lymph node syndrome mucous membrane pemphigoid myalgia nausea nonhodgkin lymphoma off label drug use pancytopenia paraneoplastic pemphigus pemphigus vulgaris pityriasis rubra pilaris primary tumor priority journal psoriasis psoriasis vulgaris psoriatic arthritis pyoderma gangrenosum Review rheumatoid arthritis rhinopharyngitis sarcoidosis scleroderma side effect skin disease skin granuloma skin lupus erythematosus skin lymphoma suppurative hidradenitis systemic lupus erythematosus tachycardia thrush toxic epidermal necrolysis treatment response upper respiratory tract infection vomiting Wegener granulomatosis wheezing antagonists and inhibitors Skin Diseases
Primary care physicians frequently encounter patients on biologic therapies, and it is valuable to understand the how biologics are used in dermatology. This article provides a practical and clinically relevant discussion on the dermatologic use of biologic medications, their dermatologic indications, mechanisms of actions, and adverse effects. © 2015 Elsevier Inc.

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