Abstract
Pharmacogenomics (PGx) offers a personalized approach to treating mental health disorders, like depression, by using an individual's genetic profile to guide medication selection and dosage. This approach can reduce trial-and-error prescribing, shorten time to remission, and decrease adverse side effects. Nurses, as frontline healthcare providers, play a crucial role in educating patients about PGx testing and incorporating it into care. There are many clinical resources available to assist with decision making when integrating PGx into routine care. As PGx testing advances, nurses must stay updated on emerging practices to optimize treatment strategies, improving patient outcomes and quality of life in mental health care.