Two distinct clones of methicillin-resistant Staphylococcus aureus (MRSA) with the same USA300 pulsed-field gel electrophoresis profile: A potential pitfall for identification of USA300 community-associated MRSA

Anders Rhod Larsen; Richard Goering; Marc Stegger; Jodi A. Lindsay; Katherine A. Gould; Jason Hinds; Marit Sørum; Henrik Westh; Kit Boye; Robert Skov

doi:10.1128/JCM.00934-09

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Two distinct clones of methicillin-resistant Staphylococcus aureus (MRSA) with the same USA300 pulsed-field gel electrophoresis profile: A potential pitfall for identification of USA300 community-associated MRSA

Anders Rhod Larsen, Richard Goering, Marc Stegger, Jodi A. Lindsay, Katherine A. Gould, Jason Hinds, Marit Sørum, Henrik Westh, Kit Boye and Robert Skov

Journal of clinical microbiology, Vol.47(11), pp.3765-3768

11/2009

DOI: https://doi.org/10.1128/JCM.00934-09

PMCID: PMC2772603

PMID: 19759225

Abstract

Microbiology (medical)

Analysis of methicillin-resistant Staphylococcus aureus (MRSA) characterized as USA300 by pulsed-field gel electrophoresis identified two distinct clones. One was similar to community-associated USA300 MRSA (ST8-IVa, t008, and Panton-Valentine leukocidin positive). The second (ST8-IVa, t024, and PVL negative) had different molecular characteristics and epidemiology, suggesting independent evolution. We recommend spa typing and/or PCR to discriminate between the two clones.

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Title: Two distinct clones of methicillin-resistant Staphylococcus aureus (MRSA) with the same USA300 pulsed-field gel electrophoresis profile
Creators: Anders Rhod Larsen (Author) - Statens Serum Institut;LEO Pharma AS
Richard Goering (Author) - Department of Medical Microbiology and Immunology
Marc Stegger (Author) - Statens Serum Institut
Jodi A. Lindsay (Author) - St. George's University of London
Katherine A. Gould (Author) - St. George's University of London
Jason Hinds (Author) - St. George's University of London
Marit Sørum (Author) - Statens Serum Institut
Henrik Westh (Author) - University of Copenhagen
Kit Boye (Author) - University of Copenhagen
Robert Skov (Author) - Statens Serum Institut
Additional links: Bumgardner, J.D.; Puckett, A.D.
Publication Details: Journal of clinical microbiology, Vol.47(11), pp.3765-3768
Series: 47
Number of pages: 4
Identifiers: 991005929811602656
Academic Unit: Med. Microbiology & Immunology
Language: English
Resource Type: Journal article

Two distinct clones of methicillin-resistant Staphylococcus aureus (MRSA) with the same USA300 pulsed-field gel electrophoresis profile: A potential pitfall for identification of USA300 community-associated MRSA

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