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Visualization of alpha9 acetylcholine receptor expression in hair cells of transgenic mice containing a modified bacterial artificial chromosome
Journal article   Peer reviewed

Visualization of alpha9 acetylcholine receptor expression in hair cells of transgenic mice containing a modified bacterial artificial chromosome

Jian Zuo, Jason Treadaway, Tyler Buckner and Bernd Fritzsch
Proceedings of the National Academy of Sciences - PNAS, Vol.96(24), pp.14100-14105
11/23/1999
PMID: 10570205

Abstract

Bacteria Cells Deoxyribonucleic acid DNA Ears & hearing Hair Neurology
  The alpha9 acetylcholine receptor (A AChR) is specifically expressed in hair cells of the inner ear and is believed to be involved in synaptic transmission between efferent nerves and hair cells. Using a recently developed method, we modified a bacterial artificial chromosome containing the mouse A AChR gene with a reporter gene encoding green fluorescent protein (GFP) to generate transgenic mice.

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